Probiotics in inflammatory bowel disease: microbial modulation and therapeutic prospects

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dc.catalogadorgjm
dc.contributor.authorVallejos Gálvez, Omar Patricio
dc.contributor.authorBueno Ramírez, Susan
dc.contributor.authorKalergis Parra, Alexis Mikes
dc.date.accessioned2025-03-20T16:14:16Z
dc.date.available2025-03-20T16:14:16Z
dc.date.issued2025
dc.description.abstractInflammatory bowel disease (IBD) is a chronic inflammatory disorder that represents a significant public health challenge worldwide. This multifactorial condition results from complex interactions among genetic, environmental, immune, and microbial factors. Some beneficial microbes, known as probiotics, have been identified as promising therapeutic agents for inflammatory conditions, such as IBD. In this review, we explore the potential of probiotics as a therapeutic strategy for managing IBD. Probiotics have shown promise due to their ability to modulate the gut microbiota, regulate histamine levels, and enhance vitamin D metabolism, thereby promoting a tolerant immune profile and reducing inflammation. While the exact mechanisms underlying these benefits remain incompletely understood, probiotics represent a novel and emerging approach for alleviating the exacerbated inflammation characteristic of this disorder.
dc.format.extent12 páginas
dc.fuente.origenSCOPUS
dc.identifier.doi10.1016/j.molmed.2024.12.005
dc.identifier.issn1471-499X
dc.identifier.scopusidSCOPUS_ID:85215106853
dc.identifier.urihttps://doi.org/10.1016/j.molmed.2024.12.005
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/102879
dc.information.autorucFacultad de Ciencias Biológicas; Vallejos Gálvez, Omar Patricio; S/I; 215421
dc.information.autorucFacultad de Ciencias Biológicas; Bueno Ramírez, Susan; 0000-0002-7551-8088; 113541
dc.information.autorucEscuela de Medicina; Kalergis Parra, Alexis Mikes; 0000-0001-7622-5263; 90610
dc.language.isoen
dc.nota.accesocontenido parcial
dc.revistaTrends in Molecular Medicine
dc.rightsacceso restringido
dc.subjectDysbiosis
dc.subjectHistamine
dc.subjectIBD
dc.subjectInflammation
dc.subjectProbiotics
dc.subjectVitamin D
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleProbiotics in inflammatory bowel disease: microbial modulation and therapeutic prospects
dc.typepreprint
sipa.codpersvinculados215421
sipa.codpersvinculados113541
sipa.codpersvinculados90610
sipa.trazabilidadSCOPUS;2025-02-02
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