Complete remission of nephrotic syndrome associated with carcinoma of the cervix after treatment of the tumor. Report of two cases
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Date
2012
Journal Title
Journal ISSN
Volume Title
Publisher
SOC MEDICA SANTIAGO
Abstract
Nephrotic syndrome secondary to paraneoplastic glomerulopathies is exceptional. We are aware of only three cases reported of cervical carcinomas associated with nephrotic syndrome. Two women, aged 40 and 79 years, presented with nephrotic syndrome. The first had a membranous nephropathy and the second was not biopsied. The first women had a metrorrhagia after 8 months of unsuccessful therapy with corticosteroids and immunosuppressive drugs. An advanced cervical carcinoma with lymph node metastases was found. In the second patient, a cervical carcinoma and hematometra was discovered two months after diagnosis of a nephrotic syndrome. The syndrome subsided completely, nine months after radiotherapy and chemotherapy in the first patient and 10 months after hysterectomy in the second patient. (Rev Med Chile 2012; 140: 1580-1584).
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Keywords
Chemoradiotherapy, Chemotherapy, adjuvant, Nephrotic syndrome, Uterine cervical neoplasms, MEMBRANOUS NEPHROPATHY, PARANEOPLASTIC GLOMERULOPATHIES, CANCER, MALIGNANCY, GLOMERULONEPHRITIS, RECEPTOR, THERAPY, ANTIGEN