SARCOID-LIKE GRANULOMATOUS MYOSITIS-ASSOCIATED HYPERCALCEMIA. AN INFREQUENT CASE TO CONSIDER

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dc.contributor.authorUslar, Thomas
dc.contributor.authorOlmos, Roberto
dc.contributor.authorGodoy-Santin, Jaime
dc.contributor.authorMellado, Patricio
dc.contributor.authorGonzalez, Gilberto
dc.date.accessioned2025-01-20T22:17:36Z
dc.date.available2025-01-20T22:17:36Z
dc.date.issued2021
dc.description.abstractPTH-independent hypercalcemia due to granulomatous disease is well-documented and sarcoidosis is the most characteristic disease, although there are others. We describe a case of sarcoid-like granulomatous myositis. An 87-year-old man was referred with tetraparesis and hypercalcemia (albumin-corrected calcium of 13.4 mg/dl) following a trip to the Caribbean. The evaluation showed a suppressed PTH, 25-hydroxy vitamin D of 7.5 ng/ml, F-18-FDG PET/CT showed markedly increased uptake in intercostal, back, shoulder, buttock and thigh muscles and a deltoid biopsy confirmed extensive granulomatous myositis. He was prescribed glucocorticoids which resulted in normalized plasma calcium levels and complete recovery from tetraparesis. Sarcoid-like granulomatous myositis should be incorporated into the differential diagnosis of PTH-independent hypercalcemia, especially in the absence of clinical features of sarcoidosis and with special emphasis on the use of F-18-FDG PET/CT to ensure a correct approach.
dc.fuente.origenWOS
dc.identifier.eissn1669-9106
dc.identifier.issn0025-7680
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/94553
dc.identifier.wosidWOS:000662247300023
dc.issue.numero3
dc.language.isoen
dc.pagina.final466
dc.pagina.inicio462
dc.revistaMedicina-buenos aires
dc.rightsacceso restringido
dc.subjecthypercalcemia
dc.subjectsarcoid-like granulomatous myositis
dc.subjectgranulomatous disease
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleSARCOID-LIKE GRANULOMATOUS MYOSITIS-ASSOCIATED HYPERCALCEMIA. AN INFREQUENT CASE TO CONSIDER
dc.typeartículo
dc.volumen81
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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