Evaluation of new natural compound formulations on the modification of metabolic syndrome components among overweight adults

Simple item page
dc.contributor.authorEbensperger, Roberto
dc.contributor.authorMoreno, Manuel
dc.contributor.authorPlaza, Cristian
dc.contributor.authorBridi, Raquel
dc.date.accessioned2025-01-20T21:00:58Z
dc.date.available2025-01-20T21:00:58Z
dc.date.issued2022
dc.description.abstractOverweight and obesity, increasingly frequent conditions in Chile and the world, are defined as chronic diseases characterized by the excessive accumulation of body fat, that can be detrimental to health. Excess body fat is the main pathogenic factor for the development of insulin resistance and metabolic syndrome, the latter characterized by a cluster of metabolic abnor-malities that increase risk of metabolic diseases and cardiovascular mortality. The objective of this preliminary cross-sectional, observational study was to evaluate a new formulation of natural compounds, Delphinol (R), resveratrol and oleanolic acid, against metabolic syndrome components in a young population with excess weight, through the intake during 22 weeks of the new formulation. The evaluation was carried out based on the clinical and anthropometric status of 20 volunteer subjects (both gender, 18 to 30 years and BMI26 to 42), medical evaluation and laboratory tests using each metabolic syndrome component (abdominal obesity, triglycerides, HDL, blood pressure y fasting glicaemia). It was observed that with the daily intake of this formulation there was a significant reduction in blood glucose levels, HOMA-IR index, triglycerides and an increase in HDL-cholesterol. These preliminary results would translate into a benefit in the health status of overweight and obese individuals, which would impact on reducing rates of metabolic syndrome. Thus, slowing down the progression of chronic diseases such as diabetes and dyslipidemia, and also contributing to decreasing the associated cardiometabolic risk.
dc.fuente.origenWOS
dc.identifier.doi10.4067/S0717-75182022000700667
dc.identifier.issn0717-7518
dc.identifier.urihttps://doi.org/10.4067/S0717-75182022000700667
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/92791
dc.identifier.wosidWOS:000904310000001
dc.issue.numero6
dc.language.isoen
dc.pagina.final673
dc.pagina.inicio667
dc.revistaRevista chilena de nutricion
dc.rightsacceso restringido
dc.subjectMetabolic Syndrome
dc.subjectObesity
dc.subjectOleanolic acid
dc.subjectPoliphenols
dc.subjectResveratrol
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleEvaluation of new natural compound formulations on the modification of metabolic syndrome components among overweight adults
dc.typeartículo
dc.volumen49
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
Files
Collections
Artículos de revistas