American Society of Hematology 2021 guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19

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dc.contributor.authorCuker, Adam
dc.contributor.authorTseng, Eric K.
dc.contributor.authorNieuwlaat, Robby
dc.contributor.authorAngchaisuksiri, Pantep
dc.contributor.authorBlair, Clifton
dc.contributor.authorDane, Kathryn
dc.contributor.authorDavila, Jennifer
dc.contributor.authorDeSancho, Maria T.
dc.contributor.authorDiuguid, David
dc.contributor.authorGriffin, Daniel O.
dc.contributor.authorKahn, Susan R.
dc.contributor.authorKlok, Frederikus A.
dc.contributor.authorLee, Alfred Ian
dc.contributor.authorNeumann, Ignacio
dc.contributor.authorPai, Ashok
dc.contributor.authorPai, Menaka
dc.contributor.authorRighini, Marc
dc.contributor.authorSanfilippo, Kristen M.
dc.contributor.authorSiegal, Deborah
dc.contributor.authorSkara, Mike
dc.contributor.authorTouri, Kamshad
dc.contributor.authorAkl, Elie A.
dc.contributor.authorAkl, Imad Bou
dc.contributor.authorBoulos, Mary
dc.contributor.authorBrignardello-Petersen, Romina
dc.contributor.authorCharide, Rana
dc.contributor.authorChan, Matthew
dc.contributor.authorDearness, Karin
dc.contributor.authorDarzi, Andrea J.
dc.contributor.authorKolb, Philipp
dc.contributor.authorColunga-Lozano, Luis E.
dc.contributor.authorMansour, Razan
dc.contributor.authorMorgano, Gian Paolo
dc.contributor.authorMorsi, Rami Z.
dc.contributor.authorNoori, Atefeh
dc.contributor.authorPiggott, Thomas
dc.contributor.authorQiu, Yuan
dc.contributor.authorRoldan, Yetiani
dc.contributor.authorSchuenemann, Finn
dc.contributor.authorStevens, Adrienne
dc.contributor.authorSolo, Karla
dc.contributor.authorVentresca, Matthew
dc.contributor.authorWiercioch, Wojtek
dc.contributor.authorMustafa, Reem A.
dc.contributor.authorSchuenemann, Holger J.
dc.date.accessioned2025-01-20T23:54:40Z
dc.date.available2025-01-20T23:54:40Z
dc.date.issued2021
dc.description.abstractBackground: Coronavirus disease 2019 (COVID-19)-related critical illness and acute illness are associated with a risk of venous thromboembolism (VTE).
dc.description.abstractObjective: These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients, clinicians, and other health care professionals in decisions about the use of anticoagulation for thromboprophylaxis for patients with COVID-19-related critical illness and acute illness who do not have confirmed or suspected VTE.
dc.description.abstractMethods: ASH formed a multidisciplinary guideline panel and applied strict management strategies to minimize potential bias from conflicts of interest. The panel included 3 patient representatives. The McMaster University GRADE Centre supported the guideline-development process, including performing systematic evidence reviews (up to 19 August 2020). The panel prioritized clinical questions and outcomes according to their importance for clinicians and patients. The panel used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach, including GRADE Evidence-to-Decision frameworks, to assess evidence and make recommendations, which were subject to public comment.
dc.description.abstractResults: The panel agreed on 2 recommendations. The panel issued conditional recommendations in favor of prophylactic-intensity anticoagulation over intermediate-intensity or therapeutic-intensity anticoagulation for patients with COVID-19-related critical illness or acute illness who do not have confirmed or suspected VTE.
dc.description.abstractConclusions: These recommendations were based on very low certainty in the evidence, underscoring the need for high-quality, randomized controlled trials comparing different intensities of anticoagulation. They will be updated using a living recommendation approach as new evidence becomes available.
dc.fuente.origenWOS
dc.identifier.doi10.1182/bloodadvances.2020003763
dc.identifier.eissn2473-9537
dc.identifier.issn2473-9529
dc.identifier.urihttps://doi.org/10.1182/bloodadvances.2020003763
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/95041
dc.identifier.wosidWOS:000733732500001
dc.issue.numero3
dc.language.isoen
dc.pagina.final888
dc.pagina.inicio872
dc.revistaBlood advances
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleAmerican Society of Hematology 2021 guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19
dc.typeartículo
dc.volumen5
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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