The relationship of clinical, cognitive and social measures in schizophrenia: A preliminary finding combining measures in probands and relatives

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dc.contributor.authorHuepe, David
dc.contributor.authorRiveros, Rodrigo
dc.contributor.authorManes, Facundo
dc.contributor.authorCouto, Blas
dc.contributor.authorHurtado, Esteban
dc.contributor.authorCetkovich, Marcelo
dc.contributor.authorEscobar, Maria
dc.contributor.authorVergara, Viviana
dc.contributor.authorParrao, Teresa
dc.contributor.authorIbanez, Agustin
dc.date.accessioned2024-01-10T12:44:10Z
dc.date.available2024-01-10T12:44:10Z
dc.date.issued2012
dc.description.abstractThis study examines performance of schizophrenia patients, unaffected relatives and controls in social cognition, cognitive and psychiatric scales looking for possible markers of vulnerability in schizophrenia. Performance of schizophrenia patients from multiplex families, first-degree relatives, and matched controls was compared and, subsequently, discriminant analysis method was used for identifying the best predictors for group membership. By using Multigroup Discriminant Analyses on the three groups, the best predictors were PANSS, Premorbid Adjustment Scale, Faux Pas test, and a face/emotion categorizing task. This model obtained 82% correct global classification, suggesting that the combination of psychiatric scales and neuropsychological/social cognition tasks are the best approach for characterizing this disease. Although preliminary, our results suggest that social cognition tasks are robust markers of schizophrenia family impairments, and that combining clinical, social and neuropsychological measures is the best approach to asses patients and relatives vulnerability.
dc.fechaingreso.objetodigital2024-05-10
dc.format.extent14 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1155/2012/194159
dc.identifier.eissn1875-8584
dc.identifier.issn0953-4180
dc.identifier.pubmedidMEDLINE:22425724
dc.identifier.urihttps://doi.org/10.1155/2012/194159
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/77652
dc.identifier.wosidWOS:000302981500007
dc.information.autorucPsicología;Hurtado E ;S/I;16876
dc.information.autorucBachillerato;Riveros R;S/I;19156
dc.issue.numero2
dc.language.isoen
dc.nota.accesocontenido completo
dc.pagina.final150
dc.pagina.inicio137
dc.publisherHINDAWI LTD
dc.revistaBEHAVIOURAL NEUROLOGY
dc.rightsacceso abierto
dc.subjectSchizophrenia
dc.subjectmultiplex family
dc.subjectsocial cognition
dc.subjectneuropsychology
dc.subjectfirst degree relatives
dc.subjectFAMILIAL LIABILITY
dc.subjectNEGATIVE SYMPTOMS
dc.subjectASPERGER-SYNDROME
dc.subjectMIND
dc.subjectDEFICITS
dc.subjectRECOGNITION
dc.subjectPSYCHOSIS
dc.subjectONSET
dc.subjectENDOPHENOTYPES
dc.subjectEXPRESSION
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleThe relationship of clinical, cognitive and social measures in schizophrenia: A preliminary finding combining measures in probands and relatives
dc.typeartículo
dc.volumen25
sipa.codpersvinculados16876
sipa.codpersvinculados19156
sipa.indexWOS
sipa.trazabilidadCarga SIPA;09-01-2024
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