Documenting the diversity of the Namibian Ju|'hoansi intestinal microbiome

dc.contributor.authorTruter, Mia
dc.contributor.authorKoopman, Jessica E.
dc.contributor.authorJordaan, Karen
dc.contributor.authorTsamkxao, Leon Oma
dc.contributor.authorCowan, Don A.
dc.contributor.authorUnderdown, Simon J.
dc.contributor.authorRamond, Jean-Baptiste
dc.contributor.authorRifkin, Riaan F.
dc.date.accessioned2025-01-20T17:08:23Z
dc.date.available2025-01-20T17:08:23Z
dc.date.issued2024
dc.description.abstractWe investigate the bacterial and fungal composition and functionality of the Ju|'hoansi intestinal microbiome (IM). The Ju|'hoansi are a hunter-gatherer community residing in northeastern Namibia. They formerly subsisted by hunting and gathering but have been increasingly exposed to industrial dietary sources, medicines, and lifestyle features. They present an opportunity to study the evolution of the human IM in situ, from a predominantly hunter-gatherer to an increasingly Western urban-forager-farmer lifestyle. Their bacterial IM resembles that of typical hunter-gatherers, being enriched for genera such as Prevotella, Blautia, Faecalibacterium, Succinivibrio, and Treponema. Fungal IM inhabitants include animal pathogens and plant saprotrophs such as Fusarium, Issatchenkia, and Panellus. Our results suggest that diet and culture exert a greater influence on Ju|'hoansi IM composition than age, self-identified biological sex, and medical history. The Ju|'hoansi exhibit a unique core IM composition that diverges from the core IMs of other populations.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.celrep.2024.113690
dc.identifier.issn2211-1247
dc.identifier.urihttps://doi.org/10.1016/j.celrep.2024.113690
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/90944
dc.identifier.wosidWOS:001167587500001
dc.issue.numero2
dc.language.isoen
dc.revistaCell reports
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleDocumenting the diversity of the Namibian Ju|'hoansi intestinal microbiome
dc.typeartículo
dc.volumen43
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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