Surpass Flow Diverter in the Treatment of Intracranial Aneurysms: A Prospective Multicenter Study

Simple item page
dc.contributor.authorWakhloo, A. K.
dc.contributor.authorLylyk, P.
dc.contributor.authorde Vries, J.
dc.contributor.authorTaschner, C.
dc.contributor.authorLundquist, J.
dc.contributor.authorBiondi, A.
dc.contributor.authorHartmann, M.
dc.contributor.authorSzikora, I.
dc.contributor.authorPierot, L.
dc.contributor.authorSakai, N.
dc.contributor.authorImamura, H.
dc.contributor.authorSourour, N.
dc.contributor.authorRennie, I.
dc.contributor.authorSkalej, M.
dc.contributor.authorBeuing, O.
dc.contributor.authorBonafe, A.
dc.contributor.authorMery, F.
dc.contributor.authorTurjman, F.
dc.contributor.authorBrouwer, P.
dc.contributor.authorBoccardi, E.
dc.contributor.authorValvassori, L.
dc.contributor.authorDerakhshani, S.
dc.contributor.authorLitzenberg, M. W.
dc.contributor.authorGounis, M. J.
dc.date.accessioned2025-01-23T21:39:43Z
dc.date.available2025-01-23T21:39:43Z
dc.date.issued2015
dc.description.abstractBACKGROUND AND PURPOSE: Incomplete occlusion and recanalization of large and wide-neck brain aneurysms treated by endovascular therapy remains a challenge. We present preliminary clinical and angiographic results of an experimentally optimized Surpass flow diverter for treatment of intracranial aneurysms in a prospective, multicenter, nonrandomized, single-arm study.
dc.description.abstractMATERIALS AND METHODS: At 24 centers, 165 patients with 190 intracranial aneurysms of the anterior and posterior circulations were enrolled. The primary efficacy end point was the percentage of intracranial aneurysms with 100% occlusion on 6-month DSA. The primary safety end point was neurologic death and any stroke through a minimum follow-up of 6 months.
dc.description.abstractRESULTS: Successful flow-diverter delivery was achieved in 161 patients with 186 aneurysms (98%); the mean number of devices used per aneurysm was 1.05. Clinical follow-up (median, 6 months) of 150 patients (93.2%), showed that the primary safety end point occurred in 18 subjects. Permanent neurologic morbidity and mortality were 6% and 2.7%, respectively. Morbidity occurred in 4% and 7.4% of patients treated for aneurysms of the anterior and posterior circulation, respectively. Neurologic death during follow-up was observed in 1.6% and 7.4% of patients with treated intracranial aneurysms of the anterior and posterior circulation, respectively. Ischemic stroke at <= 30 days, SAH at <= 7 days, and intraparenchymal hemorrhage at <= 7 days were encountered in 3.7%, 2.5%, and 2.5% of subjects, respectively. No disabling ischemic strokes at >30 days or SAH at >7 days occurred. New or worsening cranial nerve deficit was observed in 2.7%. Follow-up angiography available in 158 (86.8%) intracranial aneurysms showed 100% occlusion in 75%.
dc.description.abstractCONCLUSIONS: Clinical outcomes of the Surpass flow diverter in the treatment of intracranial aneurysms show a safety profile that is comparable with that of stent-assisted coil embolization. Angiographic results showed a high rate of intracranial aneurysm occlusion.
dc.fuente.origenWOS
dc.identifier.doi10.3174/ajnr.A4078
dc.identifier.eissn1936-959X
dc.identifier.issn0195-6108
dc.identifier.urihttps://doi.org/10.3174/ajnr.A4078
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/101607
dc.identifier.wosidWOS:000348008200018
dc.issue.numero1
dc.language.isoen
dc.pagina.final107
dc.pagina.inicio98
dc.revistaAmerican journal of neuroradiology
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleSurpass Flow Diverter in the Treatment of Intracranial Aneurysms: A Prospective Multicenter Study
dc.typeartículo
dc.volumen36
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
Files
Collections
Artículos de revistas