Invasive exercise testing in the evaluation of patients at high-risk for lung resection

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dc.contributor.authorRibas, J
dc.contributor.authorDiaz, O
dc.contributor.authorBarbera, JA
dc.contributor.authorMateu, M
dc.contributor.authorCanalis, E
dc.contributor.authorJover, L
dc.contributor.authorRoca, J
dc.contributor.authorRodriguez Roisin, R
dc.date.accessioned2024-01-10T12:06:11Z
dc.date.available2024-01-10T12:06:11Z
dc.date.issued1998
dc.description.abstractThe aim of this study was to investigate whether invasive exercise testing with gas exchange and pulmonary haemodynamic measurements could contribute to the preoperative assessment of patients with lung cancer at a high-risk for lung resection,
dc.description.abstractSixty-five patients scheduled for thoracotomy (aged 66+/-8 yrs (mean+/-SD), 64 males, forced expiratory volume in one second (FEV1) 54+/-13% predicted) were studied prospectively, High risk was defined on the basis of predicted postpneumonectomy (PPN) FEV1 and/or carbon monoxide diffusing capacity of the lung (DL,CO) <40% pred, Arterial blood gas measurements were performed in all patients at rest and during exercise, In 46 patients, pulmonary haemodynamic measurements were also performed at rest and during exercise. Predicted postoperative (PPO) values for FEV1 and DL,CO were calculated according to quantitative lung scanning and the amount of resected parenchyma,
dc.description.abstractThere were four postoperative deaths (6.2% mortality rate) and postoperative cardiorespiratory complications developed in 31 (47.7%) patients. Patients with respiratory complications only differed from patients without or with minimal (arrhythmia) complications in FEV1,PPO. Peak O-2 uptake and haemodynamic variables were similar in both groups, The four patients who died had a lower FEV1;PPO, a lower DL,CO;PPO and a greater decrease in arterial oxygen tension during exercise, compared with the remaining patients.
dc.description.abstractIn conclusion, the forced expiratory volume in one second, together with the extent of parenchymal resection and perfusion of the affected lung, are useful parameters to identify patients at greatest risk of postoperative complications among those at a high-risk for lung resection, In these patients, pulmonary haemodynamic measurements appear to have no discriminatory value, whereas gas exchange measurements during exercise may help to identify patients with higher mortality risk.
dc.fechaingreso.objetodigital2024-05-15
dc.format.extent7 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1183/09031936.98.12061429
dc.identifier.issn0903-1936
dc.identifier.pubmedidMEDLINE:9877504
dc.identifier.urihttps://doi.org/10.1183/09031936.98.12061429
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/76128
dc.identifier.wosidWOS:000077815100036
dc.information.autorucMedicina;Díaz O;S/I;78564
dc.issue.numero6
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final1435
dc.pagina.inicio1429
dc.publisherMUNKSGAARD INT PUBL LTD
dc.revistaEUROPEAN RESPIRATORY JOURNAL
dc.rightsacceso restringido
dc.subjectlung neoplasm
dc.subjectobstructive lung disease
dc.subjectpneumonectomy
dc.subjectpostoperative complications
dc.subjectpulmonary artery catheterization
dc.subjectPULMONARY-FUNCTION
dc.subjectMEDITERRANEAN POPULATION
dc.subjectPREOPERATIVE ASSESSMENT
dc.subjectOXYGEN-CONSUMPTION
dc.subjectCOMPLICATIONS
dc.subjectPREDICTOR
dc.subjectMORTALITY
dc.subjectCANCER
dc.subjectCANDIDATES
dc.subjectCARCINOMA
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleInvasive exercise testing in the evaluation of patients at high-risk for lung resection
dc.typeartículo
dc.volumen12
sipa.codpersvinculados78564
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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