MRI Pulse Sequence for Quantifying Magnetic Nanoparticles From Highly Distorted Static Field: View Line

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dc.contributor.authorLiu, Shuang
dc.contributor.authorQiu, Wenqi
dc.contributor.authorDella Maggiora, Gabriel
dc.contributor.authorKuwahata, Akihiro
dc.contributor.authorIrarrazaval, Pablo
dc.contributor.authorSekino, Masaki
dc.date.accessioned2025-01-20T16:07:23Z
dc.date.available2025-01-20T16:07:23Z
dc.date.issued2024
dc.description.abstractIn order to use magnetic resonance imaging (MRI) as a quantification tool for pre-clinical research involving high concentrations of magnetic nanoparticles (MNPs), a static field map can serve as the basis for subsequent quantitative analysis. However, the magnetic fields generated by high concentrations of MNPs can cause failure in conventional field mapping techniques. This study introduces a novel sequence for producing static field maps. This method has been demonstrated through the acquisition of 7T-MRI data and simulation data for ferucarbotran with a range of iron concentration from 27.9 to 3.48 mu g/mu L. The reconstructed interpolated field map and the theoretical field map showed a high degree of similarity, with a normalized mean error of 23.85% for phantom experiments and 12.02% for animal experiments using a rat. The quantification of the MNP concentration was also satisfactory, particularly considering that it was performed in areas, where the signal is completely lost.
dc.description.funderMinistry of Education, Cul- ture, Sports, Science and Technology (MEXT), Quantum Leap (Q-LEAP) Flagship Program
dc.fuente.origenWOS
dc.identifier.doi10.1109/TMAG.2024.3426948
dc.identifier.eissn1941-0069
dc.identifier.issn0018-9464
dc.identifier.urihttps://doi.org/10.1109/TMAG.2024.3426948
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/89999
dc.identifier.wosidWOS:001322634500018
dc.issue.numero10
dc.language.isoen
dc.revistaIeee transactions on magnetics
dc.rightsacceso restringido
dc.subjectArtificial intelligence
dc.subjectimage processing
dc.subjectmagnetic nanoparticles (MNPs)
dc.subjectmagnetic resonance imaging (MRI)
dc.subjectArtificial intelligence
dc.subjectimage processing
dc.subjectmagnetic nanoparticles (MNPs)
dc.subjectmagnetic resonance imaging (MRI)
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleMRI Pulse Sequence for Quantifying Magnetic Nanoparticles From Highly Distorted Static Field: View Line
dc.typeartículo
dc.volumen60
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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