Clinical Outcomes in Vitrectomized versus Non-vitrectomized Eyes in Patients with Primary Vitreoretinal Lymphoma

Simple item page
dc.contributor.authorLiberman, Paulina
dc.contributor.authorFrancis, Jasmine H.
dc.contributor.authorMehrotra, Karnika
dc.contributor.authorTian, Jing
dc.contributor.authorMcGarrey, Mark P.
dc.contributor.authorSobol, Ethan K.
dc.contributor.authorThorne, Jennifer E.
dc.contributor.authorAronow, Mary E.
dc.contributor.authorBerkenstock, Meghan K.
dc.date.accessioned2025-01-20T20:21:54Z
dc.date.available2025-01-20T20:21:54Z
dc.date.issued2023
dc.description.abstractAim To evaluate if there is a difference in the clinical course of primary vitreoretinal lymphoma (PVRL) in vitrectomized versus non-vitrectomized eyes. Methods Observational multicenter retrospective case series of patients diagnosed with PVRL between 2007 and 2019, at three tertiary centers. The main outcomes were relapse rates, inflammatory parameters, and best-corrected visual acuities (BCVA). Statistical methods used were an adjusted generalized estimating equation model, and a proportional Cox model. Results Eighty patients (150 eyes) were followed for a median of 1.7 years. At presentation, there were no clinical differences between the groups. The relapse rate was 0.091/eye-year (EY) for vitrectomized eyes and 0.087/EY for non-vitrectomized eyes (p = .35). Vitrectomized eyes had better BCVA than non-vitrectomized eyes (p < .001). Conclusions Vitrectomy had no effect on the relapse rate in eyes with PVRL. However, the decrease in vitreous cell and debris led to vitrectomized eyes having better visual acuity than non-vitrectomized eyes.
dc.fuente.origenWOS
dc.identifier.doi10.1080/09273948.2022.2033794
dc.identifier.eissn1744-5078
dc.identifier.issn0927-3948
dc.identifier.urihttps://doi.org/10.1080/09273948.2022.2033794
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/92650
dc.identifier.wosidWOS:000761231100001
dc.issue.numero3
dc.language.isoen
dc.pagina.final500
dc.pagina.inicio496
dc.revistaOcular immunology and inflammation
dc.rightsacceso restringido
dc.subjectPrimary vitreoretinal lymphoma
dc.subjectvitrectomy
dc.subjectocular lymphoma
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleClinical Outcomes in Vitrectomized versus Non-vitrectomized Eyes in Patients with Primary Vitreoretinal Lymphoma
dc.typeartículo
dc.volumen31
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
Files
Collections
Artículos de revistas