Multi-stage process for chemotherapy scheduling and effective capacity determination

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dc.contributor.authorCataldo, Alejandro
dc.contributor.authorSufan, Sebastian
dc.contributor.authorLorca, Alvaro
dc.contributor.authorAndresen, Max
dc.contributor.authorSanchez, Cesar
dc.contributor.authorSaure, Antoine
dc.date.accessioned2025-01-20T20:22:01Z
dc.date.available2025-01-20T20:22:01Z
dc.date.issued2023
dc.description.abstractA novel solution approach is developed for the scheduling of chemotherapy sessions at cancer treatment centers. The problem is divided into two subproblems determining the day (interday scheduling) and the time slots (intraday scheduling), respectively. The interday subproblem is solved by a model that allows for effective treatment center capacity choices while the intraday subproblem is addressed using two optimization models. New patient arrivals and treatment protocols specifying the latest starting date and session spacing are sources of uncertainty. Unlike other existing approaches, the proposed method incorporates the concept of effective treatment capacity which facilitates the interaction between the interday and intraday subproblems allowing them to be solved sequentially and iteratively to thus achieve much more resource-efficient solutions. A case study using real data from a Chilean cancer center to conduct comparative simulations of its manual scheduling methods and the proposed methodology found that the latter almost always performed better, often significantly so, on makespan, resource utilization, overtime, and patient diversion metrics.
dc.fuente.origenWOS
dc.identifier.doi10.1111/itor.13117
dc.identifier.eissn1475-3995
dc.identifier.issn0969-6016
dc.identifier.urihttps://doi.org/10.1111/itor.13117
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/92656
dc.identifier.wosidWOS:000745119200001
dc.issue.numero1
dc.language.isoen
dc.pagina.final180
dc.pagina.inicio151
dc.revistaInternational transactions in operational research
dc.rightsacceso restringido
dc.subjecthealthcare operations
dc.subjectchemotherapy
dc.subjectpatient scheduling
dc.subjectcapacity planning
dc.subjectoptimization
dc.subjectsimulation
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleMulti-stage process for chemotherapy scheduling and effective capacity determination
dc.typeartículo
dc.volumen30
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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