Outcome of renal transplantation in patients with autosomal dominant polycystic kidney disease

Simple item page
dc.contributor.authorVega, Jorge
dc.contributor.authorLira, Daniel
dc.contributor.authorMedel, Simon
dc.contributor.authorBetancour, Pablo
dc.contributor.authorGoecke, Helmuth
dc.contributor.authorCarrasco, Alejandra
dc.date.accessioned2024-01-10T13:51:41Z
dc.date.available2024-01-10T13:51:41Z
dc.date.issued2012
dc.description.abstractBackground: Patients with autosomal dominant polycystic kidney disease (ADPKD) have a better survival in chronic dialysis than patients with other etiologies of renal failure. It has been suggested that extra-renal manifestations of ADPKD may increase the odds of complications and mortality, if these patients are transplanted. Aim: To determine whether survival and complications in transplanted patients with ADPKD are different from kidney graft recipients with other etiologies of renal failure. Subjects and Methods: Four hundred six patients with kidney transplantation were followed in three hospitals between 1976 and 2011 and 19 were carriers of ADPKD. The latter were matched by type of donor, gender, age and date of kidney transplant, with 38 graft recipients with other etiologies of renal failure. Results: Graft and patient 1, 5, 10 and 15 years survival were similar in both groups. Hospitalizations due to viral infections and sepsis were more common in patients with ADPKD. There were no differences in the rate of acute rejection, delayed graft function, cancer, gastrointestinal disorders and hospitalizations due to cardiovascular diseases. The frequency of graft loss due to death with a functioning kidney was similar between both groups. Conclusions: Patient and graft survival in transplanted patients with ADPKD were similar to patients with other etiologies of renal failure. The rate and type of complications were similar between groups with the exception of hospitalizations due to sepsis and viral infections, which were more common in ADPKD patients. (Rev Med Chile 2012; 140: 990-998).
dc.fechaingreso.objetodigital2024-05-28
dc.format.extent9 páginas
dc.fuente.origenWOS
dc.identifier.doi10.4067/S0034-98872012000800004
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.pubmedidMEDLINE:23282771
dc.identifier.urihttps://doi.org/10.4067/S0034-98872012000800004
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/79618
dc.identifier.wosidWOS:000309152000004
dc.information.autorucMedicina;Goecke H;S/I;135642
dc.issue.numero8
dc.language.isoit
dc.nota.accesoContenido completo
dc.pagina.final998
dc.pagina.inicio990
dc.publisherSOC MEDICA SANTIAGO
dc.revistaREVISTA MEDICA DE CHILE
dc.rightsacceso abierto
dc.subjectKidney transplantation
dc.subjectMorbidity
dc.subjectMortality
dc.subjectPolycystic kidney
dc.subjectautosomal dominant
dc.subjectSURVIVAL
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleOutcome of renal transplantation in patients with autosomal dominant polycystic kidney disease
dc.typeartículo
dc.volumen140
sipa.codpersvinculados135642
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Outcome of renal transplantation in patients with autosomal dominant polycystic kidney disease.pdf
Size:
5.74 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas