Snakes Isogeometric Analysis (SIGA): Towards accurate and flexible geometrical models of the respiratory airways

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dc.contributor.authorOrtiz-Puerta, David
dc.contributor.authorCox, Agustin
dc.contributor.authorHurtado, Daniel E.
dc.date.accessioned2025-01-20T21:04:44Z
dc.date.available2025-01-20T21:04:44Z
dc.date.issued2022
dc.description.abstractThe construction of accurate patient-specific geometries from medical images is critical to achieving predictive numerical simulations of the respiratory system. However, the generation of surface representations of the airway tree is very challenging due to their complex morphology. In this work, we present a novel framework for creating Non-Uniform Rational B-Splines surface models of the respiratory airways. Our method relies on solving the variational formulation of the Snakes segmentation problem using Isogeometric Analysis (SIGA). We validate the SIGA method by comparing the resulting surface mesh against those delivered by two benchmark surface-fitting methods based on control-point projection. Our results confirm that SIGA outperforms the benchmark methods in creating surface models from computed-tomography images of a normal and a diseased lung. Further, we show that SIGA meshes adapt well to pathological airways with non-convex cross-sections where traditional surface-fitting methods fail. We envision that the geometrical flexibility and accuracy of SIGA will enhance the creation of computational models of the respiratory system under healthy and diseased conditions. (C) 2022 Elsevier B.V. All rights reserved.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.cma.2022.114841
dc.identifier.eissn1879-2138
dc.identifier.issn0045-7825
dc.identifier.urihttps://doi.org/10.1016/j.cma.2022.114841
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/93254
dc.identifier.wosidWOS:000821092400005
dc.language.isoen
dc.revistaComputer methods in applied mechanics and engineering
dc.rightsacceso restringido
dc.subjectActive-contour fitting
dc.subjectIsogeometric analysis
dc.subjectRespiratory airways
dc.subjectSnakes model
dc.subjectMulti-patch NURBS
dc.titleSnakes Isogeometric Analysis (SIGA): Towards accurate and flexible geometrical models of the respiratory airways
dc.typeartículo
dc.volumen394
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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