In-hospital mortality after ST-segment elevation myocardial infarction according to reperfusion therapy

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dc.contributor.authorPrieto, Juan Carlos
dc.contributor.authorSanhueza, Consuelo
dc.contributor.authorMartinez, Nicolas
dc.contributor.authorNazzala, Carolina
dc.contributor.authorCorbalan, Ramon
dc.contributor.authorCavada, Gabriel
dc.contributor.authorLanas, Fernando
dc.contributor.authorBartolucci, Jorge
dc.contributor.authorCampos, Pabla
dc.date.accessioned2025-01-21T01:05:11Z
dc.date.available2025-01-21T01:05:11Z
dc.date.issued2008
dc.description.abstractBackground: Primary angioplasty is considered the best repefusion therapy in The treatment of ST-segment elevation))myocardial infarction (STEMI). However, thrombolysis the reperfusion, method most commonly used, due to its wide availability reduced costs and case of administration. Aim To compare in-hospital mortality, in STEMI patients according to repefusion therapy. Material and Methods. Patients admitted to Chilean hospitals participating in the GEMI network,from. 2001 to 2005, with STEMI were included. They were divided in three groups: a) treated with thrombolytics, b) treated with primary angioplasty, c) without reperfusion procedure. In-hospital mortality according to gender, was analized in each group, using a logistic regression method, to assess risk factors associated with mortality. Results: We included 3,255 patients. Global mortality was 9.9% (75% in men and 16.7% in women, p < 0.001). Mortality in patients treated with thrombolytics, was 10.2% (76% in men and 18.7% in women, p < 0.01). The figure for patients treated with primary angioplasty, was 4.7% (2.5% in men and 13% in women, p < 0.01), and in patients without reperfusion, was 11.6% (9.8% in men and in 15.4% women, p < 0.01). In each group women were older, had a higher prevalence of hypertension and a higher percentage of Killip 3-4 infarctions. Logistic regression showed that angioplasty) compared with no repefusion, was associated with a reduced mortality only in men. The use of thrombolytics in women was associated with a higher mortality. Conclusions: Primary angioplasty was the reperfusion therapy associated to the lower mortality in STEMI. Use of thrombolytics in women was associated with a higher mortality rate than in non reperfused women
dc.fuente.origenWOS
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/95847
dc.identifier.wosidWOS:000255012700001
dc.issue.numero2
dc.language.isoen
dc.pagina.final150
dc.pagina.inicio143
dc.revistaRevista medica de chile
dc.rightsacceso restringido
dc.subjectAngioplasty
dc.subjectmyocardial infarction
dc.subjectmyocardial reperfusion
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleIn-hospital mortality after ST-segment elevation myocardial infarction according to reperfusion therapy
dc.typeartículo
dc.volumen136
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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