Angle Anatomy and Glaucoma in Patients With Boston Keratoprosthesis

Simple item page
dc.catalogadorgjm
dc.contributor.authorSilva, Rafaella Nascimento e
dc.contributor.authorTaniguchi, Elise V.
dc.contributor.authorCruzat Corssen, Andrea
dc.contributor.authorPaschalis, Eleftherios I.
dc.contributor.authorPasquale, Louis R.
dc.contributor.authorColby, Kathryn A.
dc.contributor.authorDohlman, Claes H.
dc.contributor.authorChodosh, James
dc.contributor.authorShen, Lucy Q.
dc.date.accessioned2023-07-17T17:45:09Z
dc.date.available2023-07-17T17:45:09Z
dc.date.issued2020
dc.description.abstractPurpose: To quantitatively analyze the angle anatomy in eyes with a Boston type 1 keratoprosthesis (KPro) using anterior segment optical coherence tomography (AS-OCT) and to assess the diagnostic ability of AS-OCT in KPro-associated glaucoma. Methods: AS-OCT (RTVue) images from KPro eyes with and without glaucoma were reviewed. The angle opening distance at 500 mu m from the scleral spur (AOD500), trabecular-iris angle at 500 mu m from the scleral spur (TIA500), and trabecular-iris surface area at 500 mu m from the scleral spur (TISA500) were measured by 2 observers masked to the diagnosis. The measurements for each visible quadrant were compared between KPro eyes with and without glaucoma. Results: Twenty-two eyes with glaucoma and 17 eyes without glaucoma from 39 patients with KPro were included. Of the 4 quadrants imaged, the temporal angle was the most visible (79.5%) and angle measurements of the temporal quadrant were the only ones that differentiated the 2 groups: the mean AOD500, TIA500, and TISA500 were significantly lower in KPro eyes with glaucoma than without glaucoma (388.2 +/- 234.4 mu m vs. 624.5 +/- 310.5 mu m,P= 0.02; 26.1 +/- 14.0 degrees vs. 39.1 +/- 17.1 degrees,P= 0.03; and 0.15 +/- 0.09 mm(2)vs. 0.23 +/- 0.12 mm(2),P= 0.03; respectively). The highest area under the receiver operating characteristic curve for detecting glaucoma was 0.75 for temporal TIA500 (95% confidence interval 0.57-0.94,P= 0.02) with 50% specificity at 80% of sensitivity and a cutoff value of 37 degrees. Conclusions: The temporal angle was the most visible on AS-OCT in eyes with a KPro. Significant narrowing of the temporal angle detected on AS-OCT was associated with glaucoma in these eyes.
dc.description.funderBoston Keratoprosthesis, Massachusetts Eye and Ear
dc.description.funderTopcon
dc.description.funderNIH
dc.fechaingreso.objetodigital2023-07-17
dc.fuente.origenWOS
dc.identifier.doi10.1097/ICO.0000000000002216
dc.identifier.eissn1536-4798
dc.identifier.issn0277-3740
dc.identifier.pubmedidPMID: 31764284
dc.identifier.urihttps://doi.org/10.1097/ICO.0000000000002216
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/74188
dc.identifier.wosidWOS:000571785000011
dc.information.autorucEscuela de Medicina; Cruzat Corssen, Andrea; 0000-0002-3724-7037; 159755
dc.issue.numero6
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final719
dc.pagina.inicio713
dc.revistaCornea
dc.rightsacceso restringido
dc.subjectBoston type I keratoprosthesis
dc.subjectAnterior segment optical coherence tomography
dc.subjectAnterior chamber angle anatomy
dc.subjectGlaucoma
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleAngle Anatomy and Glaucoma in Patients With Boston Keratoprosthesis
dc.typeartículo
dc.volumen39
sipa.codpersvinculados159755
sipa.indexWoS
sipa.indexPubmed
sipa.trazabilidadWOS;05-06-2021
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
angle_anatomy_and_glaucoma.pdf
Size:
104.47 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas