Protein and peptide delivery to lungs by using advanced targeted drug delivery

Simple item page
dc.catalogadorjca
dc.contributor.authorChellappan, Dinesh Kumar
dc.contributor.authorPrasher, Parteek
dc.contributor.authorSaravanan, Vilashini
dc.contributor.authorYee, Vanessa See Vern
dc.contributor.authorChi, Wendy Chai Wen
dc.contributor.authorWong, Jia Wei
dc.contributor.authorWong, Joon Kang
dc.contributor.authorWong, Jing Tong
dc.contributor.authorWan, Wai
dc.contributor.authorChellian, Jestin
dc.contributor.authorMolugulu, Nagashekhara
dc.contributor.authorPrabu, Sakthivel Lakshmana
dc.contributor.authorIbrahim, Rania
dc.contributor.authorDarmarajan, Thiviya
dc.contributor.authorCandasamy, Mayuren
dc.contributor.authorSingh, Pankaj Kumar
dc.contributor.authorMishra, Vijay
dc.contributor.authorShastri, Madhur D.
dc.contributor.authorZacconi, Flavia C. M.
dc.contributor.authorChakraborty, Amlan
dc.contributor.authorMehta, Meenu
dc.contributor.authorGupta, Piyush Kumar
dc.contributor.authorDureja, Harish
dc.contributor.authorGulati, Monica
dc.contributor.authorSingh, Sachin Kumar
dc.contributor.authorGupta, Gaurav
dc.contributor.authorJha, Niraj Kumar
dc.contributor.authorOliver, Brian Gregory George
dc.contributor.authorDua, Kamal
dc.date.accessioned2023-08-25T20:07:23Z
dc.date.available2023-08-25T20:07:23Z
dc.date.issued2022
dc.description.abstractThe challenges and difficulties associated with conventional drug delivery systems have led to the emergence of novel, advanced targeted drug delivery systems. Therapeutic drug delivery of proteins and peptides to the lungs is complicated owing to the large size and polar characteristics of the latter. Nevertheless, the pulmonary route has attracted great interest today among formulation scientists, as it has evolved into one of the important targeted drug delivery platforms for the delivery of peptides, and related compounds effectively to the lungs, primarily for the management and treatment of chronic lung diseases. In this review, we have discussed and summarized the current scenario and recent developments in targeted delivery of proteins and peptide-based drugs to the lungs. Moreover, we have also highlighted the advantages of pulmonary drug delivery over conventional drug delivery approaches for peptide-based drugs, in terms of efficacy, retention time and other important pharmacokinetic parameters. The review also highlights the future perspectives and the impact of targeted drug delivery on peptide-based drugs in the coming decade.
dc.fechaingreso.objetodigital2023-08-25
dc.format.extent20 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.cbi.2021.109706
dc.identifier.eissn1872-7786
dc.identifier.issn0009-2797
dc.identifier.pubmedidMEDLINE:34662570
dc.identifier.urihttps://doi.org/10.1016/j.cbi.2021.109706
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/74503
dc.identifier.wosidWOS:000721109000002
dc.information.autorucEscuela de Química; Zacconi, Flavia C. M. ; 0000-0002-3676-0453; 1011127
dc.language.isoen
dc.nota.accesoContenido parcial
dc.revistaChemico-Biological Interactions
dc.rightsacceso restringido
dc.subjectDrug delivery
dc.subjectProteins
dc.subjectPeptides
dc.subjectRespiratory
dc.subjectNanotechnology
dc.subjectTargeted
dc.subjectChronic diseases
dc.subjectLung diseases
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleProtein and peptide delivery to lungs by using advanced targeted drug delivery
dc.typeartículo
dc.volumen351
sipa.codpersvinculados1011127
sipa.indexWoS
sipa.trazabilidadWOS;18-03-2022
sipa.trazabilidadORCID;2023-08-21
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Biomedical Applications.pdf
Size:
79.37 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas