Bacterial and Viral Coinfections with the Human Respiratory Syncytial Virus

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dc.article.number1293
dc.catalogadoraba
dc.contributor.authorGaspar Pacheco
dc.contributor.authorNicolás Marcelo Salvador Gálvez Arriagada
dc.contributor.authorJorge A. Soto
dc.contributor.authorCatalina A. Andrade
dc.contributor.authorAlexis Kalergis
dc.date.accessioned2024-03-04T15:19:42Z
dc.date.available2024-03-04T15:19:42Z
dc.date.issued2021
dc.description.abstractThe human respiratory syncytial virus (hRSV) is one of the leading causes of acute lower respiratory tract infections in children under five years old. Notably, hRSV infections can give way to pneumonia and predispose to other respiratory complications later in life, such as asthma. Even though the social and economic burden associated with hRSV infections is tremendous, there are no approved vaccines to date to prevent the disease caused by this pathogen. Recently, coinfections and superinfections have turned into an active field of study, and interactions between many viral and bacterial pathogens have been studied. hRSV is not an exception since polymicrobial infections involving this virus are common, especially when illness has evolved into pneumonia. Here, we review the epidemiology and recent findings regarding the main polymicrobial infections involving hRSV and several prevalent bacterial and viral respiratory pathogens, such as Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Klebsiella pneumoniae, human rhinoviruses, influenza A virus, human metapneumovirus, and human parainfluenza viruses. As reports of most polymicrobial infections involving hRSV lack a molecular basis explaining the interaction between hRSV and these pathogens, we believe this review article can serve as a starting point to interesting and very much needed research in this area.
dc.fechaingreso.objetodigital2024-06-11
dc.format.extent16 páginas
dc.fuente.origenORCID
dc.identifier.doi10.3390/microorganisms9061293
dc.identifier.eissn2076-2607
dc.identifier.urihttps://doi.org/10.3390/microorganisms9061293
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/82469
dc.information.autorucEscuela de Medicina; Kalergis Parra, Alexis Mikes; 0000-0001-7622-5263; 90610
dc.issue.numero6
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.final16
dc.pagina.inicio1
dc.revistaMicroorganisms
dc.rightsacceso abierto
dc.rights.licenseCC BY 4.0 DEED Attribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjecthRSV
dc.subjectCoinfection
dc.subjectIAV
dc.subjecthMPV
dc.subjectHPIV
dc.subjecthRV
dc.subjectS. aureus
dc.subjectP. aeruginosa
dc.subjectS. pneumoniae
dc.subjectRespiratory infections
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleBacterial and Viral Coinfections with the Human Respiratory Syncytial Virus
dc.typeartículo
dc.volumen9
sipa.codpersvinculados90610
sipa.trazabilidadORCID;2024-01-15
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