Anatomy of corpus callosum in prenatally malnourished rats

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dc.contributor.authorOlivares, Ricardo
dc.contributor.authorMorgan, Carlos
dc.contributor.authorPerez, Hernan
dc.contributor.authorHernandez, Alejandro
dc.contributor.authorAboitiz, Francisco
dc.contributor.authorSoto Moyano, Ruben
dc.contributor.authorGil, Julio
dc.contributor.authorOrtiz, Alexis
dc.contributor.authorFlores, Osvaldo
dc.contributor.authorGimeno, Miguel
dc.contributor.authorLaborda, Jesus
dc.date.accessioned2024-01-10T12:37:32Z
dc.date.available2024-01-10T12:37:32Z
dc.date.issued2012
dc.description.abstractThe effect of prenatal malnutrition on the anatomy of the corpus callosum was assessed in adult rats (45-52 days old). In the prenatally malnourished animals we observed a significant reduction of the corpus callosum total area, partial areas, and perimeter, as compared with normal animals. In addition, the splenium of corpus callosum (posterior fifth) showed a significant decrease of fiber diameters in the myelinated fibers without changing density. There was also a significant decrease in diameter and a significant increase in density of unmyelinated fibers. Measurements of perimeter's fractal dimensions from sagittal sections of the brain and corpus callosum did not show significant differences between malnourished and control animals. These findings indicate that cortico-cortical connections are vulnerable to the prenatal malnutrition, and suggest this may affect interhemispheric conduction velocity, particular), in visual connections (splenium).
dc.description.funderFONDECYT
dc.description.funderFaculty of Veterinary Sciences, University of Chile
dc.fechaingreso.objetodigital2024-05-30
dc.format.extent6 páginas
dc.fuente.origenWOS
dc.identifier.doi10.4067/S0716-97602012000100012
dc.identifier.eissn0717-6287
dc.identifier.issn0716-9760
dc.identifier.pubmedidMEDLINE:22688989
dc.identifier.urihttps://doi.org/10.4067/S0716-97602012000100012
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/76871
dc.identifier.wosidWOS:000302674500012
dc.information.autorucMedicina;Aboitiz F ;S/I;100165
dc.issue.numero1
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.final92
dc.pagina.inicio87
dc.publisherSOC BIOLGIA CHILE
dc.revistaBIOLOGICAL RESEARCH
dc.rightsacceso abierto
dc.subjectcorpus callosum
dc.subjectprenatal malnutrition
dc.subjectrat
dc.subjectsplenium
dc.subjectINTERHEMISPHERIC ASYMMETRY
dc.subjectFUNCTIONAL ALTERATIONS
dc.subjectPROTEIN-MALNUTRITION
dc.subjectEVOKED-RESPONSES
dc.subjectSEX-DIFFERENCES
dc.subjectBRAIN
dc.subjectCONNECTIONS
dc.subjectCORTEX
dc.subject.ods02 Zero Hunger
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa02 Hambre cero
dc.subject.odspa03 Salud y bienestar
dc.titleAnatomy of corpus callosum in prenatally malnourished rats
dc.typeartículo
dc.volumen45
sipa.codpersvinculados100165
sipa.indexWOS
sipa.indexScielo
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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