Synthesis of 11,12-epoxydrim-8,12-en-11-ol, 11,12-diacetoxydrimane, and warburganal from (-)-sclareol
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Date
1999
Journal Title
Journal ISSN
Volume Title
Publisher
AMER CHEMICAL SOC
Abstract
The first syntheses are reported for recently isolated drimanes 11,12-epoxydrim-8,12-en-11-ol (2) and 11,12-diacetoxydrimane (3), from (-)-sclareol (1). Furthermore, two efficient new routes to the potent bioactive warburganal (4) starting also from 1 are described.
Description
Keywords
BIOLOGICALLY-ACTIVE DRIMANES, WIEDENDIOL-B, SESQUITERPENOIDS, SPONGE