Cat-scratch Disease in the Pediatric Population

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dc.catalogadorvzp
dc.contributor.authorReyes Zaldívar, Felipe Tomas
dc.contributor.authorSandoval, Alejandra C.
dc.contributor.authorPrado Sanhueza, Maria Alejandra
dc.contributor.authorPeña Donati, Anamaria
dc.contributor.authorViviani Salgado, Tamara Nieves
dc.date.accessioned2023-08-23T20:30:38Z
dc.date.available2023-08-23T20:30:38Z
dc.date.issued2020
dc.description.abstractBackground: Bartonella henselae is the etiologic agent of cat-scratch disease, which affects the entire world population. Due to how poorly characterized the child population is, the objective was to describe the clinical behavior of this disease in children younger than 16 years of age. Methods: This was a descriptive study with prospective follow-up of all children younger than 16 years with clinical and serologic diagnoses between 2013 and 2018. Results: There were 142 patients; of these, 55.6% had localized disease, 34.5% disseminated with hepatosplenic involvement and 9.8% had atypical disease. The cases of atypical disease were prolonged febrile illness, Parinaud syndrome, subacute bacterial endocarditis/glomerulonephritis and aseptic meningitis. Cervical lymphadenopathy was the most frequent, followed by inguinal adenopathy. There were no differences between the type of manifestation and laboratory values except for a higher erythrocyte sedimentation rate tendency in patients with disseminated and/or atypical disease. The serologic titers throughout were distributed as follows: titer of 1/1024, 71.7%; titer of 1/512, 10.4% and titer of 1/256, 17.9%. Conclusions: This is, to our knowledge, the largest series of cat-scratch disease published. We demonstrate that in our environment, the inguinal location is suggestive of this disease, the disseminated presentation, frequent, and that the titers are probably much higher than in other populations, which perhaps indicates the need to re-examine the cut-off point for positivity.
dc.fechaingreso.objetodigital2023-08-23
dc.fuente.origenORCID
dc.identifier.doi10.1097/inf.0000000000002708
dc.identifier.urihttp://dx.doi.org/10.1097/inf.0000000000002708
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/74480
dc.information.autorucEscuela de Medicina ; Reyes Zaldivar Felipe Tomas ; 0000-0002-8980-8158 ; 237969
dc.information.autorucEscuela de Medicina ; Prado Sanhueza Maria Alejandra ; S/I ; 644
dc.information.autorucEscuela de Medicina ; Viviani Salgado Tamara Nieves ; S/I ; 49002
dc.information.autorucEscuela de Medicina ; Peña Donati Anamaria ; S/I ; 100172
dc.issue.numero10
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.final893
dc.pagina.inicio889
dc.revistaPediatric Infectious Disease Journal
dc.rightsacceso abierto
dc.subjectBartonella henselae
dc.subjectCat-scratch disease
dc.subjectLymphadenopathy
dc.subjectChildren
dc.subjectClinical presentation
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleCat-scratch Disease in the Pediatric Population
dc.typeartículo
dc.volumen39
sipa.codpersvinculados237969
sipa.codpersvinculados644
sipa.codpersvinculados49002
sipa.codpersvinculados100172
sipa.trazabilidadORCID;2023-08-21
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