Nefropatía aguda por fosfatos secundaria al uso de laxantes con fosfato de sodio: caso clínico-patológico

Simple item page
dc.catalogadorjlo
dc.contributor.authorÁvila Jiménez, Eduardo Rodolfo
dc.contributor.authorPurto, Dalay
dc.contributor.authorKutscher Campero, Sofía
dc.contributor.authorCornejo Valenzuela, Cristina
dc.contributor.authorSeverino Cuevas, Nicolás Felipe
dc.contributor.authorMéndez Olivieri, Gonzalo Patricio
dc.contributor.authorTagle Vargas, Rodrigo Jaime
dc.date.accessioned2023-11-10T17:45:48Z
dc.date.available2023-11-10T17:45:48Z
dc.date.issued2021
dc.description.abstractAcute phosphate nephropathy (APN) is an acute renal failure secondary to the use of oral sodium phosphate (OSP) laxatives, with a high risk of progression to chronicity. We report a 60-year-old woman with mixed connective tissue disease whose serum creatinine increased up to 2.0 mg/dL in her regular control tests, without an evident causative factor. Kidney biopsy showed numerous intratubular calcium phosphate deposits, consistent with APN. She had a history of OSP laxative intake, and a sodium phosphate enema was used before a colonoscopy performed six months earlier. The temporal association between the use of OSP laxatives and acute kidney injury, should lead to the suspicion of APN. The urine sediment is generally normal or with mild to moderate proteinuria. The diagnosis is confirmed with a kidney biopsy. Until now, there is no specific treatment for APN, thus prevention is essential. In high-risk patients for developing APN, the administration of these laxatives should be avoided.
dc.fechaingreso.objetodigital2023-10-30
dc.format.extent5 páginas
dc.fuente.origenSIPA
dc.identifier.doi10.4067/s0034-98872021000600934
dc.identifier.issn0034-9887
dc.identifier.urihttp://dx.doi.org/10.4067/s0034-98872021000600934
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75284
dc.information.autorucEscuela de Medicina; Ávila Jiménez, Eduardo Rodolfo; 0009-0007-6587-7021; 208077
dc.information.autorucEscuela de Medicina; Severino Cuevas, Nicolás Felipe; 0000-0002-9950-3606; 149398
dc.information.autorucEscuela de Medicina; Méndez Olivieri, Gonzalo Patricio; 0000-0003-4657-7107; 123121
dc.information.autorucEscuela de Medicina; Tagle Vargas, Rodrigo Jaime; 0000-0002-7756-7190; 59867
dc.issue.numero6
dc.language.isoes
dc.nota.accesoContenido completo
dc.pagina.final938
dc.pagina.inicio934
dc.revistaRevista médica de Chile
dc.rightsacceso abierto
dc.subjectAcute Kidney Injury
dc.subjectLaxatives
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleNefropatía aguda por fosfatos secundaria al uso de laxantes con fosfato de sodio: caso clínico-patológico
dc.typeinforme
dc.volumen149
sipa.codpersvinculados208077
sipa.codpersvinculados149398
sipa.codpersvinculados123121
sipa.codpersvinculados59867
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
0717-6163-rmc-149-06-0934.pdf
Size:
0 B
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas