Hematopoietic stem cell transplantation: clinical use and perspectives

Simple item page
dc.contributor.authorBarriga, Francisco
dc.contributor.authorRamirez, Pablo
dc.contributor.authorWietstruck, Angelica
dc.contributor.authorRojas, Nicolas
dc.date.accessioned2024-01-10T12:39:20Z
dc.date.available2024-01-10T12:39:20Z
dc.date.issued2012
dc.description.abstractHematopoietic stem cell transplantation is the accepted therapy of choice for a variety of malignant and non-malignant diseases in children and adults. Initially developed as rescue therapy for a patient with cancer after high doses of chemotherapy and radiation as well as the correction of severe deficiencies in the hematopoietic system, it has evolved into an adoptive immune therapy for malignancies and autoimmune disorders. The procedure has helped to obtain key information about the bone marrow environment, the biology of hematopoietic stem cells and histocompatibility. The development of this new discipline has allowed numerous groups working around the world to cure patients of diseases previously considered lethal. Together with the ever growing list of volunteer donors and umbilical cord blood banks, this has resulted in life saving therapy for thousands of patients yearly. We present an overview of the procedure from its cradle to the most novel applications, as well as the results of the HSC transplant program developed at our institution since 1989.
dc.fechaingreso.objetodigital2024-05-30
dc.format.extent10 páginas
dc.fuente.origenWOS
dc.identifier.doi10.4067/S0716-97602012000300012
dc.identifier.eissn0717-6287
dc.identifier.issn0716-9760
dc.identifier.pubmedidMEDLINE:23283440
dc.identifier.urihttps://doi.org/10.4067/S0716-97602012000300012
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/77178
dc.identifier.wosidWOS:000310478900012
dc.information.autorucMedicina;Barriga F;S/I;99712
dc.information.autorucMedicina;Ramirez P;S/I;1242
dc.information.autorucMedicina;Rojas N;S/I;119869
dc.information.autorucMedicina;Wietstruck A;S/I;100463
dc.issue.numero3
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.final316
dc.pagina.inicio307
dc.publisherSOC BIOLGIA CHILE
dc.revistaBIOLOGICAL RESEARCH
dc.rightsacceso abierto
dc.subjecthematopoietic
dc.subjectstem cells
dc.subjecttransplantation
dc.subjectallogeneic
dc.subjectUMBILICAL-CORD BLOOD
dc.subjectACQUIRED APLASTIC-ANEMIA
dc.subjectBONE-MARROW
dc.subjectUNRELATED DONORS
dc.subjectPROGENITOR CELLS
dc.subjectRECIPIENTS
dc.subjectEXPANSION
dc.subjectCHILDREN
dc.subjectOUTCOMES
dc.subjectNICHES
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleHematopoietic stem cell transplantation: clinical use and perspectives
dc.typeartículo
dc.volumen45
sipa.codpersvinculados99712
sipa.codpersvinculados1242
sipa.codpersvinculados119869
sipa.codpersvinculados100463
sipa.indexWOS
sipa.indexScielo
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Hematopoietic stem cell transplantation; clinical use and perspectives.pdf
Size:
1.25 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas