A 19 Year Analysis of Small Mammals Associated with Human Hantavirus Cases in Chile

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dc.contributor.authorTorres-Perez, Fernando
dc.contributor.authorEduardo Palma, R.
dc.contributor.authorBoric-Bargetto, Dusan
dc.contributor.authorVial, Cecilia
dc.contributor.authorFerres, Marcela
dc.contributor.authorVial, Pablo A.
dc.contributor.authorMartinez-Valdebenito, Constanza
dc.contributor.authorPavletic, Carlos
dc.contributor.authorParra, Alonso
dc.contributor.authorMarquet, Pablo A.
dc.contributor.authorMertz, Gregory J.
dc.date.accessioned2025-01-23T21:10:50Z
dc.date.available2025-01-23T21:10:50Z
dc.date.issued2019
dc.description.abstractSmall mammals present in areas where hantavirus cardiopulmonary syndrome (HCPS) cases had occurred in central and southern Chile were captured and analyzed to evaluate the abundance of rodents and seroprevalence rates of antibodies to Andes orthohantavirus (ANDV). Sampling areas ranged from the Coquimbo to Aysen regions (30-45 degrees S approx.) regions. Ninety-two sites in peridomestic and countryside areas were evaluated in 19 years of sampling. An antibody against ANDV was detected by strip immunoassay in 58 of 1847 specimens captured using Sherman traps. Of the eleven species of rodents sampled, Abrothrix olivacea, Oligoryzomys longicaudatus and Abrothrix hirta were the most frequently trapped. O. longicaudatus had the highest seropositivity rate, and by logistic regression analysis, O. longicaudatus of at least 60 g had 80% or higher probability to be seropositive. Sex, age and wounds were significantly related to seropositivity only for O. longicaudatus. Across administrative regions, the highest seropositivity was found in the El Maule region (34.8-36.2 degrees S), and the highest number of HCPS cases was registered in the Aysen region. Our results highlight the importance of long term and geographically extended studies, particularly for highly fluctuating pathogens and their reservoirs, to understand the implications of the dynamics and transmission of zoonotic diseases in human populations.
dc.fuente.origenWOS
dc.identifier.doi10.3390/v11090848
dc.identifier.eissn1999-4915
dc.identifier.urihttps://doi.org/10.3390/v11090848
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100866
dc.identifier.wosidWOS:000487962400011
dc.issue.numero9
dc.language.isoen
dc.revistaViruses-basel
dc.rightsacceso restringido
dc.subjectAndes orthohantavirus
dc.subjectChile
dc.subjecthantavirus cardiopulmonary syndrome
dc.subjecthantavirus spatial distribution
dc.subjectOligoryzomys longicaudatus
dc.subjectperidomestic
dc.subjectrodent reservoir
dc.subjectseroprevalence
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleA 19 Year Analysis of Small Mammals Associated with Human Hantavirus Cases in Chile
dc.typeartículo
dc.volumen11
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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