Maternal care of the whole litter improves the success rate of diabetes in pregnancy in rats

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dc.contributor.authorFloriano, Juliana Ferreira
dc.contributor.authorBarbosa, Angelica Mercia Pascon
dc.contributor.authorde Oliveira, Rafael Guilen
dc.contributor.authorVega, Sofia
dc.contributor.authorCatinelli, Bruna Bologna
dc.contributor.authorGarcia, Gabriela Azevedo
dc.contributor.authorReyes, David Rafael
dc.contributor.authorSobrevia, Luis
dc.contributor.authorRudge, Marilza Vieira Cunha
dc.contributor.authorDIAMATER Study Grp
dc.date.accessioned2025-01-20T21:01:01Z
dc.date.available2025-01-20T21:01:01Z
dc.date.issued2022
dc.description.abstractInduction of diabetes mellitus by streptozotocin (STZ) in rats at birth is of high mortality and low success rate when male puppies are separated from females, prioritizing females breastfeeding. Cross-parental care of the entire litter and SZT-induced diabetes up to 12 h post-birth become with high success rate, low animal death, and females with glycaemia > 140 mg/dL on the 90 postnatal day. Cross-parental care is more effective in STZ-induction of diabetes, which is maintained during pregnancy (diabetes in pregnancy), than the conventional protocol of male separation at birth.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.placenta.2022.11.002
dc.identifier.eissn1532-3102
dc.identifier.issn0143-4004
dc.identifier.urihttps://doi.org/10.1016/j.placenta.2022.11.002
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/92805
dc.identifier.wosidWOS:000903913100006
dc.language.isoen
dc.pagina.final45
dc.pagina.inicio42
dc.revistaPlacenta
dc.rightsacceso restringido
dc.subject.ods05 Gender Equality
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa05 Igualdad de género
dc.subject.odspa03 Salud y bienestar
dc.titleMaternal care of the whole litter improves the success rate of diabetes in pregnancy in rats
dc.typeartículo
dc.volumen130
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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