Cucurbit[7]uril as a Supramolecular Catalyst in Base-Catalyzed Reactions. Experimental and Theoretical Studies on Carbonate and Thiocarbonate Hydrolysis Reactions

Fierro, Angelica; Garcia-Rio, Luis; Arancibia-Opazo, Sandra; Alcazar, Jackson J.; Santos, Jose G.; Aliaga, Margarita E.

Cucurbit[7]uril as a Supramolecular Catalyst in Base-Catalyzed Reactions. Experimental and Theoretical Studies on Carbonate and Thiocarbonate Hydrolysis Reactions

Date

2021

Authors

Fierro, Angelica

Garcia-Rio, Luis

Arancibia-Opazo, Sandra

Alcazar, Jackson J.

Santos, Jose G.

Aliaga, Margarita E.

Abstract

Cucurbit[7]uril (CB7) catalyzes the hydrolysis reaction of bis(4-nitrophenyl)carbonate (1) but inhibits that of bis(4-nitrophenyl)thiocarbonate (2). Two relevant CB7 effects are proposed, a base-catalyst mediated by the CB7 portal and an inhibitory role attributed to the lower interaction of the thiocarbonyl group with the solvent in the host cavity, respectively.