Gills de novo assembly reveals oxidative stress, unfolded protein, and immune response on red cusk-eel (<i> Genypterus</i> chilensis ) under thermal stress

Simple item page
dc.contributor.authorDettleff, Phillip
dc.contributor.authorToloza, Carla
dc.contributor.authorFuentes, Marcia
dc.contributor.authorAedo, Jorge
dc.contributor.authorZuloaga, Rodrigo
dc.contributor.authorEstrada, Juan Manuel
dc.contributor.authorMolina, Alfredo
dc.contributor.authorValdes, Juan Antonio
dc.date.accessioned2025-01-20T16:18:06Z
dc.date.available2025-01-20T16:18:06Z
dc.date.issued2024
dc.description.abstractThe heat waves on the South Pacific coast could lead to thermal stress in native fish. The red cusk-eel ( Genypterus chilensis ) is relevant for Chilean artisanal fisheries and aquaculture diversification. This study examined the effect of high-temperature stress in the gills of G. chilensis in control (14 degrees C) and high-temperature stress (19 degrees C) conditions. High-temperature stress induces a significant increase in gills cortisol levels. Additionally, oxidative damage was observed in gills (protein carbonylation and lipoperoxidation). RNA-seq data was used to build the first transcriptome assembly of gills in this species (23,656 annotated transcripts). A total of 1138 downregulated and 1531 up-regulated transcripts were observed in response to high-temperature stress in gills. The enrichment analysis showed immune response and replication enriched processes (on down-regulated transcripts), and processes related to the folding of proteins, endoplasmic reticulum, and transporter activity (on upregulated transcripts). The present study showed how gills could be affected by high-temperature stress.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.marenvres.2024.106440
dc.identifier.eissn1879-0291
dc.identifier.issn0141-1136
dc.identifier.urihttps://doi.org/10.1016/j.marenvres.2024.106440
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/90631
dc.identifier.wosidWOS:001220998900001
dc.language.isoen
dc.revistaMarine environmental research
dc.rightsacceso restringido
dc.subjectRNA-seq
dc.subjectHigh temperature
dc.subjectTeleost
dc.subjectHeat waves
dc.subjectOxidative damage
dc.subjectGene expression
dc.titleGills de novo assembly reveals oxidative stress, unfolded protein, and immune response on red cusk-eel (<i> Genypterus</i> chilensis ) under thermal stress
dc.typeartículo
dc.volumen196
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
Files
Collections
Artículos de revistas