Does a clinical prediction rule anticipate the diagnosis for streptococcal pharyngitis in children aged 2 to 15?

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dc.contributor.authorKatzulovic, Lorena
dc.contributor.authorGarcia, Patricia
dc.contributor.authorWozniak, Aniela
dc.contributor.authorVillarroel, Luis
dc.contributor.authorHirsch, Tamara
dc.contributor.authorConcha, Ida
dc.contributor.authorCatalan, Silvia
dc.contributor.authorCifuentes, Lorena
dc.date.accessioned2024-01-10T12:38:23Z
dc.date.available2024-01-10T12:38:23Z
dc.date.issued2018
dc.description.abstractBackground: The etiology of a streptococcal pharyngitis must be documented by laboratory techniques to avoid unnecessary antimicrobial treatment, but this strategy increases cost for the patient. Available scores applied in children or adults are imperfect. Aim: To develop a clinical prediction rule to aid the diagnostic process of streptococcal pharyngitis (SP) in children in a low-resource setting. Methods: Three hundred and eighteen patients aged 2 to 15 years who were evaluated for suspected SP at the Pediatric Emergency Department and the Pediatric Ambulatory Unit of Red Salud UC-Christus entered the study. A throat culture and a rapid antigen detection test for Streptococcus pyogenes were obtained from each patient. Data were analyzed for possible clinical predictors of SP with univariate and multiple regression analyses. Results: Seventy-three cases of SP were diagnosed (23.9%). In the univariate analysis, fever was inversely associated with SP (p = 0.002). Odynophagia, palatal petechiae, and season of the year (autumn and winter) were positively associated with SP (p = 0.007, p < 0.001 and p = 0.03 respectively). In multiple regression analysis the models did not have sufficient power to predict streptococcal etiology. Conclusion: Clinical predictors, even those systematically included in clinical prediction rules, did not show sufficient predictive power to safely include or exclude SP in this setting, and thus, it is necessary to improve access to confirmatory tests.
dc.fechaingreso.objetodigital2024-06-18
dc.format.extent7 páginas
dc.fuente.origenWOS
dc.identifier.eissn0717-6341
dc.identifier.issn0716-1018
dc.identifier.pubmedidMEDLINE:30724993
dc.identifier.urihttps://doi.org/10.4067/s0716-10182018000500476
dc.identifier.wosidWOS:000452408600002
dc.information.autorucMedicina;Catalan S;S/I;69953
dc.information.autorucMedicina;Cifuentes L;S/I;70068
dc.information.autorucMedicina;Concha I;S/I;74586
dc.information.autorucMedicina;García P;S/I;73909
dc.information.autorucMedicina;Hirsch T;S/I;99387
dc.information.autorucMedicina;Karzulovic L;S/I;132805
dc.information.autorucMedicina;Villarroel L;S/I;77182
dc.information.autorucMedicina;Wozniak A;S/I;1008612
dc.issue.numero5
dc.language.isoes
dc.nota.accesoContenido completo
dc.pagina.final482
dc.pagina.inicio476
dc.publisherSOC CHILENA INFECTOLOGIA
dc.revistaREVISTA CHILENA DE INFECTOLOGIA
dc.rightsacceso abierto
dc.subjectStreptococcus pyogenes
dc.subjectpharyngitis
dc.subjectclinical prediction rule
dc.subjectchildren
dc.subjectMANAGEMENT
dc.subjectGUIDELINES
dc.subjectSETTINGS
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleDoes a clinical prediction rule anticipate the diagnosis for streptococcal pharyngitis in children aged 2 to 15?
dc.typeartículo
dc.volumen35
sipa.codpersvinculados69953
sipa.codpersvinculados70068
sipa.codpersvinculados74586
sipa.codpersvinculados73909
sipa.codpersvinculados99387
sipa.codpersvinculados132805
sipa.codpersvinculados77182
sipa.codpersvinculados1008612
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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