A snapshot of cancer in Chile II: an update on research, strategies and analytical frameworks for equity, innovation and national development

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dc.article.number95
dc.catalogadoraba
dc.contributor.authorVacarezza, Cristóbal
dc.contributor.authorAraneda, Julieta
dc.contributor.authorGonzález Hevia, Pamela Andrea
dc.contributor.authorArteaga, Oscar
dc.contributor.authorMarcelain, Katherine
dc.contributor.authorCastellon, Enrique A.
dc.contributor.authorPeriera, Ana
dc.contributor.authorKhoury, Maroun
dc.contributor.authorMüller, Bettina
dc.contributor.authorLecaros, Juan A.
dc.contributor.authorSalas, Sofia P.
dc.contributor.authorRiquelme Pérez, Arnoldo
dc.contributor.authorCorvalán R., Alejandro
dc.contributor.authorde la Jara, Jorge J.
dc.contributor.authorFerreccio, Catterina
dc.contributor.authorGoic B., Carolina
dc.contributor.authorNervi Nattero, Bruno
dc.contributor.authorRoa, Juan C.
dc.contributor.authorOwen, Gareth Ivor
dc.date.accessioned2024-12-30T13:35:10Z
dc.date.available2024-12-30T13:35:10Z
dc.date.issued2024
dc.date.updated2024-12-22T01:04:55Z
dc.description.abstractAbstract Introduction Chile has achieved developed nation status and boasts a life expectancy of 81 + years; however, the healthcare and research systems are unprepared for the social and economic burden of cancer. One decade ago, the authors put forward a comprehensive analysis of cancer infrastructure, together with a series of suggestions on research orientated political policy. Objectives Provide an update and comment on policy, infrastructure, gender equality, stakeholder participation and new challenges in national oncology. Assess the funding and distribution of cancer investigation. Present actions for the development of oncology research, innovation and patient care. Methods Triangulating objective system metrics of economic, epidemiological, private and public sector resources together with policy analysis, we assessed cancer burden, infrastructure, and investigation. We analyzed governmental and private-sector cancer databases, complemented by interviews with cancer stakeholders. Results Governmental policy and patient advocacy have led to the recognition of cancer burden, a cancer law, and a national cancer plan. Cancer has become the leading cause of death in Chile (59,876 cases and 31,440 cancer deaths in 2022), yet only 0.36% gross domestic product (GDP) is directed to research and development. Inequalities in treatment regimens persist. Prevention policy has lowered tobacco consumption, sugar intake via soft drinks and offered a high coverage of HPV vaccines. A high-quality cancer research community is expanding, and internationally sponsored clinical oncology trials are increasing. Conclusions The cancer law has facilitated advancement in policy. Prevention policies have impacted tobacco and sugar intake, while gender equality and care inequality have entered the public forum. Cancer research is stagnated by the lack of investment. Implementation of a cancer registry and biobanking, reinforcement of prevention strategies, development of human resources, promotion of clinical trial infrastructure and investment in new technologies must be placed as a priority to permit advancements in innovation and equitable cancer care.
dc.fechaingreso.objetodigital2024-12-19
dc.format.extent26 páginas
dc.fuente.origenAutoarchivo
dc.identifier.doi10.1186/s40659-024-00574-2
dc.identifier.issn0717-6287
dc.identifier.scopusid2-s2.0-85212390833
dc.identifier.urihttps://doi.org/10.1186/s40659-024-00574-2
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/89354
dc.identifier.wosidWOS:001380061800001
dc.information.autorucFacultad de Ciencias Biológicas; González Hevia, Pamela Andrea; 0009-0001-4402-2020; 127012
dc.information.autorucEscuela de Medicina; Riquelme Pérez, Arnoldo; 0000-0002-8259-8960; 3538
dc.information.autorucEscuela de Medicina; Goic B., Carolina; S/I; 67870
dc.information.autorucEscuela de Medicina; Nervi Nattero, Bruno; 0000-0002-3016-7261; 604
dc.information.autorucEscuela de Medicina; Owen, Gareth Ivor; 0000-0003-3807-6054; 1000459
dc.issue.numero1
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final26
dc.pagina.inicio1
dc.revistaBiological Research
dc.rightsacceso abierto
dc.rights.licenseAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectChile
dc.subjectSouth-America
dc.subjectResearch
dc.subjectPolicy
dc.subjectIncidence
dc.subjectClinical trials
dc.titleA snapshot of cancer in Chile II: an update on research, strategies and analytical frameworks for equity, innovation and national development
dc.typeartículo
dc.volumen57
sipa.codpersvinculados127012
sipa.codpersvinculados3538
sipa.codpersvinculados67870
sipa.codpersvinculados604
sipa.codpersvinculados1000459
sipa.indexScopus
sipa.indexWOS
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