Prehabilitation for Chilean frail elderly people - pre-surgical conditioning protocol - to reduce the length of stay: randomized control trial

Simple item page
dc.catalogadoraba
dc.contributor.authorContreras Ibacache, Víctor
dc.contributor.authorElgueta Le-beuffe, María Francisca
dc.contributor.authorBalde Sepulveda, Detlef Peter Mario
dc.contributor.authorAstaburuaga Jorquera, Paula Daniela
dc.contributor.authorCarrasco, Marcela
dc.contributor.authorPedemonte Trewhela, Juan Cristobal
dc.contributor.authorNicoletti Santoni, Maria Natalia
dc.contributor.authorMedina Díaz, René
dc.contributor.authorFigueroa, Constanza
dc.contributor.authorAlamos Ramirez, Mirelly De Los Angeles
dc.contributor.authorCuzmar Benítez, Valeria
dc.contributor.authorVargas Moreno, Benjamin Ignacio
dc.contributor.authorBarraza Mendizabal, Benjamin Juan Pablo
dc.contributor.authorRetamal, Claudio
dc.contributor.authorCortinez Fernandez, Luis Ignacio
dc.contributor.authorFranco, Sebastián
dc.contributor.authorAgurto, Raul
dc.contributor.authorVivanco, Catherin
dc.date.accessioned2025-04-01T13:18:39Z
dc.date.available2025-04-01T13:18:39Z
dc.date.issued2024
dc.description.abstractBackground: Frail elderly patients have a higher risk of postoperative morbidity and mortality. Prehabilitation is a potential intervention for optimizing postoperative outcomes in frail patients. We studied the impact of a prehabilitation program on length of stay (LOS) in frail elderly patients undergoing elective surgery.Methods: An RCT study was conducted. Frail patients scheduled for elective surgery were randomized to receive either pre-surgical conditioning protocol (PCP) or standard preoperative care. PCP included nursing, anesthetic, and geriatric assessment, nutritional intervention, and physical training for 4-weeks preoperatively. A nurse followed both groups until discharge criteria were met. The primary outcome was postoperative LOS. Secondary outcomes were nutritional status, preoperative frailty status (frailty phenotype-FP) after PCP, and postoperative complications up to three months categorized according to the Clavien-Dindo Classification. Means and medians between the control and intervention groups were compared, with statistical significance set at α=5%.Results: Thirty-four patients were to intervention and Thirty-seven to the control group. In the intervention group, adherence to prehabilitation was 90%. The median LOS after surgery was three days in both groups, without finding statistically significant differences between groups (P=0.754), although there was a trend towards lower LOS in the urologic surgery subgroup. We found a significant reduction in frailty status after PCP (FP<inf>pre</inf>=2.4±0.5 and FP<inf>post</inf>=1.7±0.5, P<0.001). Nutritional status significantly improved in frail patients after prehabilitation (MNA<inf>basal</inf>=9.0±2.5 and MNA<inf>post</inf>=10.6±2.6), P=0.028. The intervention group had less severe postoperative complications, which were not statistically significant.Conclusions: The PCP conducted both in-person and online, for older frail patients undergoing elective colorectal and urological surgery was not associated with shorter LOS. However, frailty status significantly improved after completing PCP.
dc.format.extent10 páginas
dc.fuente.origenORCID
dc.identifier.doi10.23736/S0375-9393.24.18245-4
dc.identifier.eissn1827-1596
dc.identifier.issn0375-9393
dc.identifier.pubmedid9836361
dc.identifier.scopusid2-s2.0-85216249878
dc.identifier.urihttps://doi.org/10.23736/S0375-9393.24.18245-4
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/103070
dc.identifier.wosidWOS:001406213600006
dc.information.autorucEscuela de Enfermería; Contreras Ibacache, Víctor; 0000-0002-6081-0430; 101258
dc.information.autorucEscuela de Medicina; Elgueta Le-beuffe, María Francisca; 0000-0001-5513-7408; 167324
dc.information.autorucEscuela de Medicina; Balde Sepulveda, Detlef Peter Mario; 0009-0003-3625-7449; 172128
dc.information.autorucEscuela de Medicina; Astaburuaga Jorquera, Paula Daniela; S/I; 237947
dc.information.autorucEscuela de Medicina; Pedemonte Trewhela, Juan Cristobal; 0000-0001-5729-065X; 119581
dc.information.autorucEscuela de Medicina; Nicoletti Santoni, Maria Natalia; S/I; 1024900
dc.information.autorucEscuela de Medicina; Vargas Moreno, Benjamin Ignacio; S/I; 1088110
dc.information.autorucEscuela de Medicina; Alamos Ramirez, Mirelly De Los Angeles; 0009-0009-8809-9757; 1004231
dc.information.autorucEscuela de Medicina; Cuzmar Benítez, Valeria; 0000-0002-6109-1263; 215768
dc.information.autorucEscuela de Medicina; Barraza Mendizabal, Benjamin Juan Pablo; S/I; 1088203
dc.information.autorucEscuela de Medicina; Cortinez Fernandez, Luis Ignacio; 0000-0001-8544-8768; 79356
dc.issue.numero12
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final1107
dc.pagina.inicio1098
dc.revistaMinerva Anestesiologica
dc.rightsacceso restringido
dc.subjectFrailty
dc.subjectPerioperative care
dc.subjectLength of stay
dc.subjectAged
dc.subjectNursing care
dc.subjectNutrition therapy
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 03 Salud y bienestar
dc.titlePrehabilitation for Chilean frail elderly people - pre-surgical conditioning protocol - to reduce the length of stay: randomized control trial
dc.typeartículo
dc.volumen90
sipa.codpersvinculados101258
sipa.codpersvinculados167324
sipa.codpersvinculados172128
sipa.codpersvinculados237947
sipa.codpersvinculados119581
sipa.codpersvinculados1024900
sipa.codpersvinculados1088110
sipa.codpersvinculados1004231
sipa.codpersvinculados215768
sipa.codpersvinculados1088203
sipa.codpersvinculados79356
sipa.trazabilidadORCID;2025-03-03
Files
Collections
Artículos de revistas