The preparation of oxygenated derivatives of ambrox and isoambrox from drimenol
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Date
2006
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Abstract
The preparation of oxygenated derivatives of ambrox and isoambrox is described. The compounds 7 alpha-hydroxy-isoambrox, 7 beta-hydroxy-isoambrox, 7 alpha-hydroxy-ambrox, 7 beta-hydroxy-ainbrox, 7-oxo-isoambrox and 7-oxo-ambrox have been synthesized from (+drimenol, readily available from the bark of Drimys winteri. The structures of the products were determined mainly by spectroscopic methods.
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Keywords
ambrox, isoambrox, ambergris