Quality of life, exercise capacity, cognition, and mental health of Chilean patients after COVID-19: an experience of a multidisciplinary rehabilitation program at a physical and rehabilitation medicine unit

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dc.contributor.authorPaez, Valeria
dc.contributor.authorRodriguez-Fernandez, Maria
dc.contributor.authorMorales, Diego
dc.contributor.authorTorres, Camillo
dc.contributor.authorArdiles, Andres
dc.contributor.authorSoza, Sergio
dc.contributor.authorBustos, Cynthia
dc.contributor.authorManriquez, Fernanda
dc.contributor.authorGarcia, Cesar
dc.contributor.authorRocco, Rossana
dc.contributor.authorLang, Morin
dc.date.accessioned2025-01-20T17:21:28Z
dc.date.available2025-01-20T17:21:28Z
dc.date.issued2023
dc.description.abstractBackground: Post-COVID disabilities, encompassing physical, cognitive, and psychological aspects, constitute the primary health sequelae for survivors. While the rehabilitation needs post COVID-19 are now well understood, each country possesses unique characteristics in terms of populations, healthcare systems, social dynamics, and economic profiles, necessitating context-specific recommendations. This study aims to address two main objectives: (1) analyze the impact of an 8-week multidisciplinary rehabilitation program on the quality of life, functional capacity, cognition, and mental health adaptations in adults recovering from COVID-19 in northern Chile, and (2) propose a personalized model for predicting program dropouts and responses.Methods: A total of 44 subjects were enrolled, forming two groups during the study: a treatment group (n = 32) and a dropout group (n = 12). The treatment group participated in the 8-week multidisciplinary rehabilitation program.Results: The results indicate that (1) After 8 weeks, the quality of life of the patients in the treatment group exhibited significant improvements reflected in all aspects of the Short Form-36 Health Survey (SF36, p < 0.005) and the total score (p < 0.001), with a concurrent decrease in dysfunctionality (p < 0.001). (2) Significant improvements were also observed in various physical performance tests, including the: 6-minute walk test, 1-min sit-to-stand, dynamometry, Tinetti balance, and Berg score (p < 0.001). Moreover, physical therapy led to a reduction in neuropathic symptoms and pain, psychological therapy reduced anxiety and depression, and language therapy enhanced memory and speech (all p < 0.05). (3) Demographic and clinical history characteristics did not predict responses to rehabilitation. (4) A regression model for predicting changes in SF-36 total score, based on physical function, physical role, general health, and mental health, was established based on the data from study (p < 0.01, adjusted R-2 = 0.893). (5) Classification models for predicting dropouts achieved 68% accuracy, with key predictors of treatment adherence including diabetes, hypertension, and dyslipidemia, Tinetti balance, physical role, and vitality of SF36, and performance on the 6-minute walk test and 1-minute sit-to-stand.Conclusions: This study demonstrates significant enhancements in quality of life, improved functional performance, and reductions in mental and cognitive burdens within an 8-week rehabilitation program. Additionally, it is possible to identify patients at risk of dropping out using cost-effective, outpatient, and clinically applicable tests.
dc.description.funderANID
dc.fuente.origenWOS
dc.identifier.doi10.3389/fresc.2023.1274180
dc.identifier.eissn2673-6861
dc.identifier.urihttps://doi.org/10.3389/fresc.2023.1274180
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/91457
dc.identifier.wosidWOS:001126982400001
dc.language.isoen
dc.revistaFrontiers in rehabilitation sciences
dc.rightsacceso restringido
dc.subjectcoronavirus
dc.subjectSARS-CoV-2
dc.subjectpost-COVID disabilities
dc.subjectrehabilitation
dc.subjectmultidisciplinary team
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleQuality of life, exercise capacity, cognition, and mental health of Chilean patients after COVID-19: an experience of a multidisciplinary rehabilitation program at a physical and rehabilitation medicine unit
dc.typeartículo
dc.volumen4
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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