Folate status in women of childbearing age in the Urban Metropolitan Region of Chile: results from the National Health Survey 2016-2017

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dc.contributor.authorBusso, Dolores
dc.contributor.authorEcheverria, Guadalupe
dc.contributor.authorPassi Solar, Alvaro
dc.contributor.authorMorales, Fernanda
dc.contributor.authorFarias, Marcelo
dc.contributor.authorMargozzini, Paula
dc.date.accessioned2024-01-10T14:22:33Z
dc.date.available2024-01-10T14:22:33Z
dc.date.issued2021
dc.description.abstractObjective: To analyse serum folate levels in women of childbearing age in the Metropolitan Region (MR) of Chile.
dc.description.abstractDesign: Cross-sectional design as part of the 2016-2017 National Health Survey (Encuesta Nacional de Salud, ENS 2016-2017), using a household-based multistage stratified random sample. Serum folate levels measured by electrochemiluminescence immunoassay in fasting venous blood samples were classified as deficient (<4 center dot 4 ng/ml), normal (4 center dot 4-20 ng/ml) or supraphysiological (>20 ng/ml).
dc.description.abstractSetting: The MR of Chile.
dc.description.abstractParticipants: Women of reproductive age (15-49 years, n 222) from the MR participated in the ENS 2016-2017.
dc.description.abstractResults: The mean, median and range of serum folate were 14 center dot 2 (se 0 center dot 4), 13 center dot 9 and 2 center dot 1-32 center dot 2 ng/ml, respectively. Folate deficiency was detected in 0 center dot 9 % of women, while 7 center dot 0 % had supraphysiological levels of the vitamin. No significant effects of age, educational level, marital status, parity, smoking status or nutritional status on serum folate levels were detected by univariate or multivariate analyses. Intake of folic acid supplements showed a significant association with serum folate levels, but only 1 center dot 2 % of women used supplements.
dc.description.abstractConclusions: Folate deficiency in women of reproductive age living in the MR of Chile is almost inexistent according to the ENS 2016-2017, suggesting that the current population-wide mandatory folic acid fortification of flour is an effective and equitable measure to prevent folate deficiency. These results support the option of maintaining current folic acid fortification in Chile, particularly based on the low adherence to supplementation regimes evidenced in other populations.
dc.description.funderMinistry of Health from Chile (Ministerio de Salud, Subsecretaria de Salud Publica)
dc.fechaingreso.objetodigital2024-04-18
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1017/S1368980020002608
dc.identifier.eissn1475-2727
dc.identifier.issn1368-9800
dc.identifier.pubmedidMEDLINE:32907649
dc.identifier.urihttps://doi.org/10.1017/S1368980020002608
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/79956
dc.identifier.wosidWOS:000608455300001
dc.information.autorucFacultad de Medicina; Farias Jofre, Marcelo Enrique; S/I; 12286
dc.issue.numero3
dc.language.isoen
dc.nota.accesocontenido completo
dc.pagina.final392
dc.pagina.inicio385
dc.publisherCAMBRIDGE UNIV PRESS
dc.revistaPUBLIC HEALTH NUTRITION
dc.rightsacceso abierto
dc.subjectFolic acid fortification
dc.subjectPlasma folate levels
dc.subjectNeural tube defects
dc.subjectReproductive age
dc.subjectChile
dc.subjectFOLIC-ACID FORTIFICATION
dc.subjectNEURAL-TUBE DEFECTS
dc.subjectREPRODUCTIVE AGE
dc.subjectUS POPULATION
dc.subjectPREVENTION
dc.subjectNUTRITION
dc.subjectPROGRAM
dc.subjectSERUM
dc.subjectMORTALITY
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleFolate status in women of childbearing age in the Urban Metropolitan Region of Chile: results from the National Health Survey 2016-2017
dc.typeartículo
dc.volumen24
sipa.codpersvinculados12286
sipa.indexWOS
sipa.indexPubmed
sipa.trazabilidadCarga SIPA;09-01-2024
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