Factors associated with survival and survival without major morbidity in very preterm infants in two neonatal networks: SEN1500 and NEOCOSUR

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dc.catalogadoryvc
dc.contributor.authorGarcía-Muñoz Rodrigo, Fermín
dc.contributor.authorFabres Biggs, Jorge Guillermo Eduardo
dc.contributor.authorTapia Illanes, José Luis
dc.contributor.authorD'apremont Ormeño, Ivonne
dc.contributor.authorSan Feliciano, Laura
dc.contributor.authorZozaya Nieto, Carlos
dc.contributor.authorFigueras Aloy, Josep
dc.contributor.authorMariani, Gonzalo
dc.contributor.authorMusante, Gabriel
dc.contributor.authorSilvera, Fernando
dc.contributor.authorZegarra, Jaime
dc.contributor.authorVento, Máximo
dc.date.accessioned2021-07-22T22:51:59Z
dc.date.available2021-07-22T22:51:59Z
dc.date.issued2021
dc.description.abstractIntroduction: Very low-birth weight (VLBW) infants represent a high-risk population for morbidity and mortality in the neonatal period. Variability in practices and outcomes between centers has been acknowledged. Multicenter benchmarking studies are useful to detect areas of improvement and constitute an interesting research tool. Objectives: The aim of the study was to determine the perinatal variables and interventions associated with survival and survival without major morbidity in VLBW infants and compare the performance of 2 large networks. Methods: This is a prospective study analyzing data collected in 2 databases, the Spanish SEN1500 and the South American NEOCOSUR networks, from January 2013 to December 2016. Inborn patients, from 24(0) to 30(6) weeks of gestational age (GA) were included. Hazard ratios for survival and survival without major morbidity until the first hospital discharge or transfer to another facility were studied by using Cox proportional hazards regression. Results: A total of 10,565 patients, 6,120 (57.9%) from SEN1500 and 4,445 (42.1%) from NEOCOSUR, respectively, were included. In addition to GA, birth weight, small for gestational age (SGA), female sex, and multiple gestation, less invasive resuscitation, and the network of origin were significant independent factors influencing survival (aHR [SEN1500 vs. NEOCOSUR]: 1.20 [95% CI: 1.15-1.26] and survival without major morbidity: 1.34 [95% CI: 1.26-1.43]). Great variability in outcomes between centers was also found within each network. Conclusions: After adjusting for covariates, GA, birth weight, SGA, female sex, multiple gestation, less invasive resuscitation, and the network of origin showed an independent effect on outcomes. Determining the causes of these differences deserves further study.
dc.fechaingreso.objetodigital2023-10-23
dc.fuente.origenWOS
dc.identifier.doi10.1159/000513079
dc.identifier.eissn1661-7819
dc.identifier.issn1661-7800
dc.identifier.pubmedidMEDLINE_ID:33631749
dc.identifier.urihttps://doi.org/10.1159/000513079
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75163
dc.identifier.wosidWOS:000625249200001
dc.information.autorucEscuela de Medicina;Fabres Biggs, Jorge Guillermo Eduardo; S/I; 71713
dc.information.autorucEscuela de Medicina;Tapia Illanes, José Luis; S/I; 99000
dc.information.autorucEscuela de Medicina;D'apremont Ormeño, Ivonne;S/I;100049
dc.issue.numero3
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final296
dc.pagina.inicio289
dc.publisherS. Karger A.G.
dc.revistaNeonatology
dc.rightsacceso restringido
dc.subjectVery low-birth weight infant
dc.subjectMorbidity
dc.subjectMortality
dc.subjectNeonatal networks
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleFactors associated with survival and survival without major morbidity in very preterm infants in two neonatal networks: SEN1500 and NEOCOSUR
dc.typeartículo
dc.volumen118
sipa.codpersvinculados71713
sipa.codpersvinculados99000
sipa.codpersvinculados100049
sipa.indexWoS
sipa.indexPubmed
sipa.trazabilidadWOS;05-06-2021
sipa.trazabilidadORCID;2023-10-23
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