Effect of psychostimulants on distinct attentional parameters in attentional deficit/hyperactivity disorder

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dc.contributor.authorLopez, J
dc.contributor.authorLopez, V
dc.contributor.authorRojas, D
dc.contributor.authorCarrasco, X
dc.contributor.authorRothhammer, P
dc.contributor.authorGarcia, R
dc.contributor.authorRothhammer, F
dc.contributor.authorAboitiz, F
dc.date.accessioned2024-01-10T13:12:33Z
dc.date.available2024-01-10T13:12:33Z
dc.date.issued2004
dc.description.abstractAlthough there is extensive literature about the effects of stimulants on sustained attention tasks in attentional deficit/hyperactivity disorder (ADHD), little is known about the effect of these drugs on other attentional tasks involving different neural systems. In this study we measured the effect of stimulants on ADHD children, both in the electroencephalographic (EEG) activity during sustained attentional tasks and in psychometric performance during selective attentional tasks. These tasks are known to rely on different cortical networks. Our results in children medicated with 10 mg of d-amphetamine administered 60 min before the study indicate (i) a significant increase in amplitude but not latency of the P300 component of the event-related potential (ERP) during the sustained attentional task and (ii) a significant improvement in the reaction times and correct responses in the selective attentional task. In addition to supporting the use of stimulants in children with attentional deficit/hyperactivity disorder, these results show a multifocal activity improvement of cortical structures linked to dopamine, and interestingly, to attention. All these analyses are framed in a wider study of diverse attentional functions in this syndrome.
dc.fechaingreso.objetodigital2024-06-19
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.eissn0717-6287
dc.identifier.issn0716-9760
dc.identifier.pubmedidMEDLINE:15515970
dc.identifier.urihttp://dx.doi.org/10.4067/S0716-97602004000300010
dc.identifier.wosidWOS:000224665500010
dc.information.autorucMedicina;Aboitiz F;S/I;100165
dc.issue.numero3
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.final468
dc.pagina.inicio461
dc.publisherSOC BIOLGIA CHILE
dc.revistaBIOLOGICAL RESEARCH
dc.rightsacceso abierto
dc.subjectattentional deficit
dc.subjectEEG
dc.subjectevent-related potentials
dc.subjecthyperactivity
dc.subjectstroop
dc.subjectp300
dc.subjectDEFICIT-HYPERACTIVITY DISORDER
dc.subjectEVENT-RELATED POTENTIALS
dc.subjectANTERIOR CINGULATE CORTEX
dc.subjectCHILDREN
dc.subjectMETHYLPHENIDATE
dc.subjectSTIMULANTS
dc.subjectSELECTION
dc.subjectLANGUAGE
dc.subjectABUSE
dc.subjectGENE
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleEffect of psychostimulants on distinct attentional parameters in attentional deficit/hyperactivity disorder
dc.typeartículo
dc.volumen37
sipa.codpersvinculados100165
sipa.indexWOS
sipa.indexScielo
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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