New treatment for faecal incontinence using zinc-aluminium ointment: a double-blind randomized trial

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dc.contributor.authorPinedo, G.
dc.contributor.authorZarate, A. J.
dc.contributor.authorInostroza, G.
dc.contributor.authorMeneses, X.
dc.contributor.authorFalloux, E.
dc.contributor.authorMolina, O.
dc.contributor.authorMolina, M. E.
dc.contributor.authorBellolio, F.
dc.contributor.authorZuniga, A.
dc.date.accessioned2024-01-10T13:15:32Z
dc.date.available2024-01-10T13:15:32Z
dc.date.issued2012
dc.description.abstractAim In a randomized double-blind study the therapeutic effect of a novel zincaluminium ointment was compared with placebo in patients with faecal incontinence.
dc.description.abstractMethod A randomized double-blind trial was performed. Patients who met the inclusion criteria were randomized to receive the ointment or a placebo. All were evaluated prior to and 3 weeks after ointment application, using the Wexner incontinence score and the Fecal Incontinence Quality of Life (FIQL) score.
dc.description.abstractResults Fifty patients were randomized and six were lost to follow-up, leaving 24 in the treatment and 20 in the placebo group. The average ages were 61.3 and 60.7 years. The respective Wexner scores prior to intervention were 16.6 and 16.7. They decreased significantly after treatment to 8.5 and 13.1 (P < 0.001 and P = 0.002 respectively). There was a significant difference in the final scores, favouring the treatment group (P = 0.001). The FIQL scores for the treatment group were also significantly better in all parameters compared with those of the placebo group.
dc.description.abstractConclusion The study shows that the zinc-aluminium based ointment decreases faecal incontinence significantly compared with placebo.
dc.fechaingreso.objetodigital2024-05-09
dc.format.extent3 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1111/j.1463-1318.2011.02728.x
dc.identifier.issn1462-8910
dc.identifier.pubmedidMEDLINE:21781231
dc.identifier.urihttps://doi.org/10.1111/j.1463-1318.2011.02728.x
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/78509
dc.identifier.wosidWOS:000302150400024
dc.information.autorucMedicina;Bellolio F ;S/I;9713
dc.information.autorucMedicina;Falloux E ;S/I;163729
dc.information.autorucMedicina;Inostroza G ;S/I;209559
dc.information.autorucMedicina;Meneses X ;S/I;81375
dc.information.autorucMedicina;Molina M;S/I;102077
dc.information.autorucMedicina;Pinedo G ;S/I;1002552
dc.information.autorucMedicina;Zarate A;S/I;15134
dc.issue.numero5
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final598
dc.pagina.inicio596
dc.publisherWILEY-BLACKWELL
dc.revistaCOLORECTAL DISEASE
dc.rightsacceso restringido
dc.subjectFecal incontinence
dc.subjectaluminum
dc.subjectrandomized trial
dc.subjectOF-LIFE SCALE
dc.subjectPREVALENCE
dc.subjectHOME
dc.subject.ods05 Gender Equality
dc.subject.odspa05 Igualdad de género
dc.titleNew treatment for faecal incontinence using zinc-aluminium ointment: a double-blind randomized trial
dc.typeartículo
dc.volumen14
sipa.codpersvinculados9713
sipa.codpersvinculados163729
sipa.codpersvinculados209559
sipa.codpersvinculados81375
sipa.codpersvinculados102077
sipa.codpersvinculados1002552
sipa.codpersvinculados15134
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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