Influence of polymeric enteral nutrition supplemented with different doses of glutamine on gut permeability in critically ill patients

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dc.contributor.authorVelasco, N
dc.contributor.authorHernandez, G
dc.contributor.authorWainstein, C
dc.contributor.authorCastillo, L
dc.contributor.authorMaiz, A
dc.contributor.authorLopez, F
dc.contributor.authorGuzman, S
dc.contributor.authorBugedo, G
dc.contributor.authorAcosta, AM
dc.contributor.authorBruhn, A
dc.date.accessioned2025-01-21T01:30:38Z
dc.date.available2025-01-21T01:30:38Z
dc.date.issued2001
dc.description.abstractOBJECTIVES: To evaluate the effect of glutamine-supplemented polymeric enteral formulas on the recovery of gut-permeability abnormalities in critically ill patients.
dc.description.abstractMETHODS: Twenty-three patients were randomized to receive a conventional casein-based enteral formula (ADN), ADN plus glutamine in a dose of 0.15 g.kg(-1).d(-1) or ADN plus 0.30 g.kg(-1).d(-1) of glutamine for 8 d. The lactulose mannitol permeability test (L/M) was performed at baseline and at the end of the study. Nineteen healthy volunteers served as controls for the L/M test.
dc.description.abstractRESULTS: An increase in permeability compared with control subjects was observed in patients at baseline (mean +/- standard error of the mean, L/M ratio: 0.11 +/- 0.03 and 0.025 +/- 0.004, respectively; P < 0.02). The L/M ratio improved after the period of enteral nutrition as a whole (initial L/M: 0.11 0.03, final L/M: 0.061 +/- 0.01; P < 0.03), but no difference was found between groups.
dc.description.abstractCONCLUSIONS: Even though polymeric enteral nutrition was associated with a significant improvement in the L/M ratio, glutamine supplementation did not show a specific influence in improving recovery of gut permeability in critically ill patients. (C) Elsevier Science Inc. 2001.
dc.fuente.origenWOS
dc.identifier.eissn1873-1244
dc.identifier.issn0899-9007
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/96841
dc.identifier.wosidWOS:000172774800001
dc.issue.numero11-12
dc.language.isoen
dc.pagina.final911
dc.pagina.inicio907
dc.revistaNutrition
dc.rightsacceso restringido
dc.subjectgut permeability
dc.subjectglutamine
dc.subjectlactulose mannitol test
dc.subjectenteral nutrition
dc.subject.ods02 Zero Hunger
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa02 Hambre cero
dc.subject.odspa03 Salud y bienestar
dc.titleInfluence of polymeric enteral nutrition supplemented with different doses of glutamine on gut permeability in critically ill patients
dc.typeartículo
dc.volumen17
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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