Features associated with the development of non-motor manifestations in Parkinson's disease

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dc.contributor.authorJuri, Carlos
dc.contributor.authorViviani, Paola
dc.contributor.authorChana, Pedro
dc.date.accessioned2024-01-10T12:38:58Z
dc.date.available2024-01-10T12:38:58Z
dc.date.issued2008
dc.description.abstractParkinson's disease (PD) is a neurodegenerative disorder, predominantly characterized by the presence of motor symptoms. However, the non motor manifestations (NMM) are a frequent complaint in the PD patients. There is a lack of information about the risk factors associated with the NMM in these patients. The aim of this study is to evaluate the prevalence of the more common NMM in a population of PD patients and to determine the features associated with its development. We! studied 124 ambulatory PD patients. NMM were defined by the presence of neuropsychiatric manifestations, cognitive disorder, autonomic dysfunction or sleep related problems. In a multivariate analysis we found that the years of evolution of the PD and the presence of cognitive dysfunction are the risk factors for the neuropsychiatric and autonomic manifestations, whereas axial impairment is a risk factor for cognitive disorders and dyskinesias is for sleep related problems. In conclusion, this study shows that the features related to the PD progression appear as the main risk factors associated with NMM.
dc.format.extent4 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1590/S0004-282X2008000100006
dc.identifier.issn0004-282X
dc.identifier.pubmedidMEDLINE:18392408
dc.identifier.urihttps://doi.org/10.1590/S0004-282X2008000100006
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/77127
dc.identifier.wosidWOS:000254580100006
dc.information.autorucMedicina;Juri C;S/I;7476
dc.information.autorucMedicina;Viviani P;S/I;729
dc.issue.numero1
dc.language.isoen
dc.nota.accesoSin adjunto
dc.pagina.final25
dc.pagina.inicio22
dc.publisherASSOC ARQUIVOS NEURO- PSIQUIATRIA
dc.revistaARQUIVOS DE NEURO-PSIQUIATRIA
dc.rightsregistro bibliográfico
dc.subjectParkinson's disease
dc.subjectnon motor manifestations
dc.subjectCOGNITIVE IMPAIRMENT
dc.subjectMOTOR
dc.subjectPOPULATION
dc.subjectDEPRESSION
dc.subjectSEVERITY
dc.subjectSYMPTOMS
dc.subjectDEMENTIA
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleFeatures associated with the development of non-motor manifestations in Parkinson's disease
dc.typeartículo
dc.volumen66
sipa.codpersvinculados7476
sipa.codpersvinculados729
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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