Total/HDL cholesterol ratio and non HDL cholesterol as predictors for increased intima media thickness
dc.contributor.author | Acevedo, Monica | |
dc.contributor.author | Kraemer, Veronica | |
dc.contributor.author | Tagle, Rodrigo | |
dc.contributor.author | Corbalan, Ramon | |
dc.contributor.author | Arnaiz, Pilar | |
dc.contributor.author | Berrios, Ximena | |
dc.contributor.author | Navarrete, Carlos | |
dc.date.accessioned | 2024-01-10T13:44:00Z | |
dc.date.available | 2024-01-10T13:44:00Z | |
dc.date.issued | 2012 | |
dc.description.abstract | Background: LDL, HDL cholesterol and triglycerides, are the most commonly used lipid cardiovascular risk predictor indicators. However population based studies have shown that non-HDL cholesterol and total/HDL cholesterol ratio are better predictors, are easy to measure and do not require fasting. Aim: To determine which lipid indicators are better determinants of subclinical atherosclerosis, measured by intima media thickness (IMT) among subjects without demonstrated atherosclerosis. Material and Methods: Lipid profile, height, weight, blood pressure and bilateral IMT measured by ultrasound with automatic border recognition software, were assessed in 770 men and 854 women aged 45 +/- 11 years, in Santiago de Chile. Results: Mean total cholesterol was 202, HDL 50, LDL 121, triglycerides 157 and non-HDL cholesterol 152 mg/dl. Total/HDL cholesterol ratio was 4.3. Mean IMT was 0.62 mm. All lipid markers were significantly correlated with IMT This correlation was higher for non-HDL cholesterol (r = 0.24, p < 0.0001) and total/HDL cholesterol ratio(r = 0.23, p < 0.0001). In both men and women, total/HDL cholesterol ratio was the best predictor of having an IMT over the 75th percentile (odds ratio 1.21, 95% confidence intervals 1.09-1.35, p < 0.01). Conclusions: Total/HDL cholesterol ratio was the best determinant of subclinical atherosclerosis. (Rev Med Chile 2012; 140: 969-976). | |
dc.fechaingreso.objetodigital | 2024-05-28 | |
dc.format.extent | 8 páginas | |
dc.fuente.origen | WOS | |
dc.identifier.doi | 10.4067/S0034-98872012000800001 | |
dc.identifier.eissn | 0717-6163 | |
dc.identifier.issn | 0034-9887 | |
dc.identifier.pubmedid | MEDLINE:23282768 | |
dc.identifier.uri | https://doi.org/10.4067/S0034-98872012000800001 | |
dc.identifier.uri | https://repositorio.uc.cl/handle/11534/78812 | |
dc.identifier.wosid | WOS:000309152000001 | |
dc.information.autoruc | Medicina;Acevedo M;S/I;81173 | |
dc.information.autoruc | Medicina;Arnaiz P;S/I;98982 | |
dc.information.autoruc | Medicina;Berrios X;S/I;98139 | |
dc.information.autoruc | Medicina;Corbalan R;S/I;98700 | |
dc.information.autoruc | Medicina;Kramer V;S/I;4946 | |
dc.information.autoruc | Medicina;Tagle R;S/I;59867 | |
dc.issue.numero | 8 | |
dc.language.iso | it | |
dc.nota.acceso | Contenido completo | |
dc.pagina.final | 976 | |
dc.pagina.inicio | 969 | |
dc.publisher | SOC MEDICA SANTIAGO | |
dc.revista | REVISTA MEDICA DE CHILE | |
dc.rights | acceso abierto | |
dc.subject | Carotid intimae-media thickness | |
dc.subject | Cholesterol | |
dc.subject | Risk factors | |
dc.subject | DENSITY LIPOPROTEIN CHOLESTEROL | |
dc.subject | CARDIOVASCULAR-DISEASE | |
dc.subject | HEART-DISEASE | |
dc.subject | RISK-FACTORS | |
dc.subject | A-I | |
dc.subject | CORONARY | |
dc.subject | APOLIPOPROTEINS | |
dc.subject | ATHEROSCLEROSIS | |
dc.subject | PREVENTION | |
dc.subject | EVENTS | |
dc.subject.ods | 03 Good Health and Well-being | |
dc.subject.odspa | 03 Salud y bienestar | |
dc.title | Total/HDL cholesterol ratio and non HDL cholesterol as predictors for increased intima media thickness | |
dc.type | artículo | |
dc.volumen | 140 | |
sipa.codpersvinculados | 81173 | |
sipa.codpersvinculados | 98982 | |
sipa.codpersvinculados | 98139 | |
sipa.codpersvinculados | 98700 | |
sipa.codpersvinculados | 4946 | |
sipa.codpersvinculados | 59867 | |
sipa.index | WOS | |
sipa.index | Scopus | |
sipa.trazabilidad | Carga SIPA;09-01-2024 |
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