Advancements in MELD Score and Its Impact on Hepatology

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dc.catalogadoryvc
dc.contributor.authorHudson, David
dc.contributor.authorValentin Cortez, Francisco Javier
dc.contributor.authorHurtado Díaz de León, Ivonne
dc.contributor.authorMalhi, Gurpreet
dc.contributor.authorRivas, Angélica
dc.contributor.authorAfzaal, Tamoor
dc.contributor.authorRad, Mahsa Rahmany
dc.contributor.authorDíaz Piga, Luis Antonio
dc.contributor.authorKhan, Mohammad Qasim
dc.contributor.authorArab Verdugo, Juan Pablo
dc.date.accessioned2025-03-18T20:53:33Z
dc.date.available2025-03-18T20:53:33Z
dc.date.issued2024
dc.description.abstractThere continues to be an ongoing need for fair and equitable organ allocation. The Model for End-Stage Liver Disease (MELD) score has evolved as a calculated framework to evaluate and allocate patients for liver transplantation objectively. The original MELD score has undergone multiple modifications as it is continuously scrutinized for its accuracy in objectively representing the clinical context of patients with liver disease. Several refinements and iterations of the score have been developed, including the widely accepted MELD-Na score. In addition, the most recent updated iteration, MELD 3.0, has been created. The MELD 3.0 calculator incorporates new variables such as patient sex and serum albumin levels and assigns new weights for serum sodium, bilirubin, international normalized ratio, and creatinine levels. It is anticipated that the use of MELD 3.0 scores will reduce overall waitlist mortality and enhance access for female liver transplant candidates. However, despite the emergence of the MELD score as one of the most objective measures for fair organ allocation, various countries and healthcare systems employ alternative methods for stratification and organ allocation. This review article will highlight the origins of the MELD score, its iterations, the current MELD 3.0, and future directions for managing liver transplantation organ allocation.
dc.fuente.origenScopus
dc.identifier.doi10.1055/a-2464-9543
dc.identifier.issn1098-8971
dc.identifier.scopusidScopus_ID: 85212572244
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/102789
dc.information.autorucEscuela de Medicina; Díaz Piga, Luis Antonio; 0000-0002-8540-4930; 179253
dc.information.autorucEscuela de Medicina; Arab Verdugo, Juan Pablo; 0000-0002-8561-396X; 132745
dc.language.isoen
dc.nota.accesocontenido parcial
dc.publisherThieme Medical Publishers, Inc.
dc.revistaSeminars in Liver Disease
dc.rightsacceso restringido
dc.subjectCirrhosis
dc.subjectHepatology
dc.subjectLiver disease
dc.subjectModel for end-stage liver disease
dc.subjectOrgan allocation
dc.subjectRisk stratification
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleAdvancements in MELD Score and Its Impact on Hepatology
dc.typeartículo
sipa.codpersvinculados179253
sipa.codpersvinculados132745
sipa.trazabilidadScopus;2025-01-05
sipa.trazabilidadORCID;2025-03-03
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