Pandemic influenza A (H1N1) in HIV-1-infected patients
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Date
2010
Journal Title
Journal ISSN
Volume Title
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Abstract
Objective: To characterize the clinical presentation, course and mortality of pandemic influenza in HIV-1-infected patients in Santiago, Chile.
Methods: Prospective observational study.
Results: Thirty patients were included (three hospitalized), 93% were on HAART, mean CD4(+) cell count was 423 cells/mu l and viral load was undetectable in 77% of patients. All patients had fever, 90% had cough, 80% had myalgias, 70% had pharyngeal congestion, 47% had coryza, 47% had odynophagia, 37% had headache and 23% had vomiting. Four patients developed pneumonia. All patients received antiviral therapy and no patient died.
Conclusions: HIV patients infected by the new influenza A pandemic (H1N1) virus behave similarly to the general population. (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins
Methods: Prospective observational study.
Results: Thirty patients were included (three hospitalized), 93% were on HAART, mean CD4(+) cell count was 423 cells/mu l and viral load was undetectable in 77% of patients. All patients had fever, 90% had cough, 80% had myalgias, 70% had pharyngeal congestion, 47% had coryza, 47% had odynophagia, 37% had headache and 23% had vomiting. Four patients developed pneumonia. All patients received antiviral therapy and no patient died.
Conclusions: HIV patients infected by the new influenza A pandemic (H1N1) virus behave similarly to the general population. (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins
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Keywords
HIV-1, influenza A, pandemic, VIRUS, EMERGENCE, HUMANS