Opioid prescribing for cancer pain in Latin America: systematic review

Simple item page
dc.contributor.authorLeiva, Ofelia
dc.contributor.authorChukwusa, Emeka
dc.contributor.authorNkhoma, Kennedy
dc.contributor.authorDittborn, Mariana
dc.contributor.authorTurrillas, Pamela
dc.contributor.authorPastrana, Tania
dc.date.accessioned2025-01-20T16:15:32Z
dc.date.available2025-01-20T16:15:32Z
dc.date.issued2024
dc.description.abstractObjective To explore opioid prescribing patterns for cancer pain in Latin America (LA).Methods A systematic review was conducted adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Relevant databases, including MEDLINE, EMBASE, PubMed, LILACS and Scielo, were searched from inception to June 2023. Empirical studies of opioid prescription patterns in adult palliative care patients with cancer pain were included. Methodological quality was assessed using the Effective Public Health Practice Project tool. Data were analysed using narrative synthesis. Descriptive statistical analyses were conducted using SPSS V.28 (IBM). Categorical variables were summarised using frequencies and percentages and continuous variables as means or medians.Results Seventeen studies from six countries were included. Ten were observational, while seven were experimental, including five randomised controlled trials (RCT) and two non-RCT. Most were low or moderate methodological quality. Out of 7809 patients, morphine (54%) and tramadol (18%) were the most prescribed opioids. The median of morphine equivalent daily dose was 26 mg (IQR 26-41).Conclusion Latin America shows lower opioid consumption rates compared with high-income countries for control pain management (CPM). More rigorous research on CPM in LA is needed. Additionally, a comprehensive review of opioid prescription patterns, including non-cancer diagnoses, is necessary.
dc.fuente.origenWOS
dc.identifier.doi10.1136/spcare-2024-004999
dc.identifier.eissn2045-4368
dc.identifier.issn2045-435X
dc.identifier.urihttps://doi.org/10.1136/spcare-2024-004999
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/90500
dc.identifier.wosidWOS:001250532800001
dc.language.isoen
dc.revistaBmj supportive & palliative care
dc.rightsacceso restringido
dc.subjectPalliative Care
dc.subjectPain
dc.subjectCancer
dc.subjectDrug administration
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleOpioid prescribing for cancer pain in Latin America: systematic review
dc.typeartículo
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
Files
Collections
Artículos de revistas