Collapsing glomerulopathy
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Date
2012
Journal Title
Journal ISSN
Volume Title
Publisher
SOC MEDICA SANTIAGO
Abstract
Collapsing glomerulopathy is a cause of nephrotic syndrome with massive proteinuria secondary to podocyte proliferation and glomerular collapse. It is characterized by an almost inevitable progression to end stage renal failure, poor response to treatment and high post-transplant recurrence. Its frequency has increased in recent years due to its common association with Human Immunodeficiency Virus (HIV) infection and the growing recognition of new etiologic agents such as drugs and parvovirus B19. Therefore, it is a disease of growing interest for clinicians. The aim of this review is to update the clinical presentation, diagnosis, pathogenesis and therapeutic alternatives of this disease. (Rev Med Chile 2012; 140: 1342-1346).
Description
Keywords
Glomerulopathies, HIV, Parvovirus, HIV-ASSOCIATED NEPHROPATHY, FOCAL SEGMENTAL GLOMERULOSCLEROSIS, EPIDEMIOLOGY