Ileal pouch-anal anastomosis in ulcerative colitis: outcomes, functional results, and quality of life in patients with more than 10-year follow-up

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dc.contributor.authorCarcamo, L.
dc.contributor.authorMiranda, P.
dc.contributor.authorZuniga, A.
dc.contributor.authorAlexander, E.
dc.contributor.authorMolina, M. E.
dc.contributor.authorUrrejola, G.
dc.contributor.authorLarach, T.
dc.contributor.authorMiguieles, R.
dc.contributor.authorBellolio, Felipe
dc.date.accessioned2024-01-10T12:39:35Z
dc.date.available2024-01-10T12:39:35Z
dc.date.issued2020
dc.description.abstractPurpose Ileal pouch-anal anastomosis (IPAA) has become the surgical procedure of choice for patients with ulcerative colitis (UC). IPAA was incorporated into our institution in 1984, and thereafter, more than 200 procedures have been performed. The functional results and morbidity of this surgery have been reported previously. However, long-term functional outcomes and quality of life have not been evaluated. Methods As a cohort study, we identified all consecutive patients who underwent IPAA for UC between 1984 and 2017 and selected those with more than 10-year follow-up. Demographic data, morbidity, and pouch survival information were obtained. Long-term functional results and quality of life were evaluated through an e-mail survey using the oresland score and the Cleveland Global Quality of Life scales, respectively. Results Of 201 patients, 116 met the inclusion criteria. Median follow-up was 20 (10-34) years. Early post-operative complications (30 days) were observed in 19 (16.4%) patients and 66 (56.9%) presented adverse events. The IPAA preservation rate at 10 and 20 years was 96.5% and 93.1%, respectively. Long-term functional scores presented a median of 6 (1-15) points. IPAA function was satisfactory in 11 (20.0%) patients, acceptable in 18 (32.7%), and deficient in 26 (47.3%). The median score for global quality of life was 0.8 (0.23-1.0) points. Conclusion IPAA as treatment for UC meets the expectations of cure of the disease, maintaining adequate long-term intestinal functionality associated with a good quality of life in most patients.
dc.description.funderPontificia Universidad Catolica
dc.fechaingreso.objetodigital2024-03-21
dc.format.extent7 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1007/s00384-020-03529-7
dc.identifier.eissn1432-1262
dc.identifier.issn0179-1958
dc.identifier.pubmedidMEDLINE:32067061
dc.identifier.urihttps://doi.org/10.1007/s00384-020-03529-7
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/77210
dc.identifier.wosidWOS:000516186800001
dc.information.autorucMedicina;Bellolio Roth Felipe;S/I;9713
dc.information.autorucMedicina;Larach Kattan Jose Tomas;S/I;131898
dc.information.autorucMedicina;Miguieles Cocco Rodrigo Alfons;S/I;1009541
dc.information.autorucMedicina;Miranda Hiriart Pablo;S/I;126188
dc.information.autorucMedicina;Molina Maldonado Miguel Estuar;S/I;167337
dc.information.autorucMedicina;Urrejola Schmied Gonzalo Ignac;S/I;199958
dc.information.autorucMedicina;Zuniga Avendano Alvaro Alfonso;S/I;72399
dc.issue.numero4
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final753
dc.pagina.inicio747
dc.publisherSPRINGER
dc.revistaINTERNATIONAL JOURNAL OF COLORECTAL DISEASE
dc.rightsacceso restringido
dc.subjectUlcerative colitis
dc.subjectIleal pouch-anal anastomosis
dc.subjectQuality of life
dc.subjectRESTORATIVE PROCTOCOLECTOMY
dc.subjectPELVIC SEPSIS
dc.subjectCOMPLICATIONS
dc.subjectIPAA
dc.subjectILEOSTOMY
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleIleal pouch-anal anastomosis in ulcerative colitis: outcomes, functional results, and quality of life in patients with more than 10-year follow-up
dc.typeartículo
dc.volumen35
sipa.codpersvinculados9713
sipa.codpersvinculados131898
sipa.codpersvinculados1009541
sipa.codpersvinculados126188
sipa.codpersvinculados167337
sipa.codpersvinculados199958
sipa.codpersvinculados72399
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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