Indirect measurement of water content in an aseptic solid substrate cultivation pilot-scale bioreactor

Simple item page
dc.contributor.authorLillo, MPY
dc.contributor.authorPerez Correa, R
dc.contributor.authorAgosin, E
dc.contributor.authorLatrille, E
dc.date.accessioned2024-01-10T13:13:50Z
dc.date.available2024-01-10T13:13:50Z
dc.date.issued2001
dc.description.abstractA lack of models and sensors for describing and monitoring large-scale solid substrate cultivation (SSC) bioreactors has hampered industrial development and application of this type of process. This study presents an indirect dynamic measurement model for a 200-kg-capacity fixed-bed SSC bioreactor under periodic agitation. Growth of the filamentous fungus Gibberella fujikuroi on wheat bran was used as a case study. Real data were preprocessed using previously reported methodology. The model uses CO, production rate and inlet air conditions to estimate average bed water content and average bed temperature. The model adequately reproduces the evolution of the average bed water content and can therefore be used as an on-line estimator in pilot-scale SSC bioreactors. To obtain a reasonable fit of the bed temperature, however, inlet air humidity measurements will have to be adjusted with a data reconciliation algorithm. Good estimation of temperature is important for the future design of improved water content estimation using state observers. The model also provides insight into understanding the complex behavior of the dynamic system, which could prove useful when establishing advanced model-based operational and control strategies. (C) 2001 John Wiley & Sons, Inc.
dc.fechaingreso.objetodigital2024-06-25
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.issn0006-3592
dc.identifier.pubmedidMEDLINE:11400105
dc.identifier.urihttps://doi.org/10.1002/bit.1024
dc.identifier.wosidWOS:000169515200005
dc.information.autorucIngeniería;Agosin E;S/I;99630
dc.information.autorucIngeniería;Pérez J;S/I;100130
dc.issue.numero1
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final51
dc.pagina.inicio44
dc.publisherJOHN WILEY & SONS INC
dc.revistaBIOTECHNOLOGY AND BIOENGINEERING
dc.rightsacceso restringido
dc.subjectaseptic cultivation
dc.subjectGibberella fujikuroi
dc.subjectmacroscopic model
dc.subjectenergy balance
dc.subjectwater balance
dc.subjectSTATE FERMENTATION
dc.subject.ods12 Responsible Consumption and Production
dc.subject.ods07 Affordable and Clean Energy
dc.subject.odspa12 Producción y consumo responsable
dc.subject.odspa07 Energía asequible y no contaminante
dc.titleIndirect measurement of water content in an aseptic solid substrate cultivation pilot-scale bioreactor
dc.typeartículo
dc.volumen76
sipa.codpersvinculados99630
sipa.codpersvinculados100130
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Indirect measurement of water content in an aseptic solid substrate cultivation pilot-scale bioreactor.pdf
Size:
2.86 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas