New Hybrid Copper Nanoparticles/Conjugated Polyelectrolyte Composite with Antibacterial Activity

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dc.contributor.authorJessop, Ignacio A.
dc.contributor.authorPerez, Yasmin P.
dc.contributor.authorJachura, Andrea
dc.contributor.authorNunez, Hipolito
dc.contributor.authorSaldias, Cesar
dc.contributor.authorIsaacs, Mauricio
dc.contributor.authorTundidor-Camba, Alain
dc.contributor.authorTerraza, Claudio A.
dc.contributor.authorAraya-Duran, Ingrid
dc.contributor.authorCamarada, Maria B.
dc.contributor.authorCarcamo-Vega, Jose J.
dc.date.accessioned2025-01-20T23:55:04Z
dc.date.available2025-01-20T23:55:04Z
dc.date.issued2021
dc.description.abstractIn the search for new materials to fight against antibiotic-resistant bacteria, a hybrid composite from metallic copper nanoparticles (CuNPs) and a novel cationic pi-conjugated polyelectrolyte (CPE) were designed, synthesized, and characterized. The CuNPs were prepared by chemical reduction in the presence of CPE, which acts as a stabilizing agent. Spectroscopic analysis and electron microscopy showed the distinctive band of the metallic CuNP surface plasmon and their random distribution on the CPE laminar surface, respectively. Theoretical calculations on CuNP/CPE deposits suggest that the interaction between both materials occurs through polyelectrolyte side chains, with a small contribution of its backbone electron density. The CuNP/CPE composite showed antibacterial activity against Gram-positive (Staphylococcus aureus and Enterococcus faecalis) and Gram-negative (Escherichia coli and Salmonella enteritidis) bacteria, mainly attributed to the CuNPs' effect and, to a lesser extent, to the cationic CPE.
dc.fuente.origenWOS
dc.identifier.doi10.3390/polym13030401
dc.identifier.eissn2073-4360
dc.identifier.urihttps://doi.org/10.3390/polym13030401
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/95069
dc.identifier.wosidWOS:000615430200001
dc.issue.numero3
dc.language.isoen
dc.revistaPolymers
dc.rightsacceso restringido
dc.subjectconjugated polyelectrolyte
dc.subjectcopper nanoparticles
dc.subjectnanoparticles stabilization
dc.subjectnanoparticles-polyelectrolyte hybrid composite
dc.subjectantibacterial activity
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleNew Hybrid Copper Nanoparticles/Conjugated Polyelectrolyte Composite with Antibacterial Activity
dc.typeartículo
dc.volumen13
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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