Three-dimensional electrical impedance tomography (EIT) to study regional ventilation/perfusion (V/Q̇) ratios in anesthetized pigs

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dc.catalogadorpva
dc.contributor.authorLarrabee, Shannon
dc.contributor.authorNugen, Sarah
dc.contributor.authorBruhn, Alejandro
dc.contributor.authorStowe, Symon
dc.contributor.authorAdler, Andy
dc.contributor.authorMartin-Flores, Manuel
dc.contributor.authorAraos, Joaquin
dc.date.accessioned2025-03-06T19:40:13Z
dc.date.available2025-03-06T19:40:13Z
dc.date.issued2023
dc.description.abstractThis study aimed to develop a 3D method for assessing V/Q̇ ratios in a pig model of hemodynamic perturbations using electrical impedance tomography (EIT). In order to evaluate whether the physiological coherence of changes in EIT-derived V/Q̇ ratios, global EIT-derived V/Q̇ mismatch were compared with global gold-standards. The study found regional heterogeneity in the distribution of V/Q̇ ratios in both the ventrodorsal and craniocaudal directions. Although global EIT-derived indices of V/Q̇ mismatch consistently underestimated both low and high V/Q̇ mismatch compared to global gold standards, the direction of the change was similar. We have made the software available at no cost for other researchers to use. Future studies should compare regional V/Q̇ ratios determined by our method against other regional, high-resolution methods such as SPECT or PET scan.
dc.fechaingreso.objetodigital2025-03-06
dc.format.extent18 páginas
dc.fuente.origenORCID
dc.identifier.doi10.21203/rs.3.rs-2828854/v1
dc.identifier.scopusidSCOOUS_ID:85167642564
dc.identifier.urihttps://doi.org/10.21203/rs.3.rs-2828854/v1
dc.identifier.urihttp://www.scopus.com/inward/record.url?eid=2-s2.0-85167642564&partnerID=MN8TOARS
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/102415
dc.information.autorucEscuela de Medicina; Bruhn, Alejandro; 0000-0001-8034-1937; 741
dc.language.isoen
dc.nota.accesocontenido completo
dc.publisherResearch Square
dc.revistaResearch Square
dc.rightsacceso abierto
dc.rights.licenseCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleThree-dimensional electrical impedance tomography (EIT) to study regional ventilation/perfusion (V/Q̇) ratios in anesthetized pigs
dc.typepreprint
sipa.codpersvinculados741
sipa.trazabilidadORCID;2025-03-03
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