Prevalence of non-alcoholic fatty liver disease and its association with lifestyle habits in adults in Chile. A cross-sectional study from the National Health Survey 2016-2017

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dc.contributor.authorPettinelli Rocha, Paulina Pilar
dc.contributor.authorFernández Mincone, Tiziana
dc.contributor.authorAguirre Polanco, Carolina
dc.contributor.authorBarrera Martínez, Francisco José
dc.contributor.authorRiquelme Pérez, Arnoldo
dc.contributor.authorFernandez-Verdejo, Rodrigo
dc.date.accessioned2024-10-21T14:53:59Z
dc.date.available2024-10-21T14:53:59Z
dc.date.issued2023
dc.description.abstract© The Authors 2023.Non-alcoholic fatty liver disease (NAFLD) represents an excessive fat accumulation within the liver, usually associated with excess body weight. A liver biopsy is the gold standard for diagnosis, but it is inapplicable in population-based studies. In large populations, non-invasive methods could be used, which may also serve to identify potential protective factors. We aimed to: [a] estimate NAFLD prevalence in the adult population in Chile by using non-invasive methods; and [b] determine the association between the presence of NAFLD and lifestyle habits. The National Health Survey of Chile 2016-2017 was analysed. We included individuals aged 21-75 years, without infectious diseases nor risky alcohol consumption. NAFLD was detected by either Fatty Liver Index (FLI; considers circulating triglycerides, circulating gamma-glutamyl-transferase, body mass index, and waist circumference), Lipid Accumulation Product (LAP; considers sex, circulating triglycerides, and waist circumference), or their combination. Lifestyle habits were determined by questionnaires. We included 2,774 participants, representative of 10,599,094 [9,831,644-11,366,544] adults in Chile. NAFLD prevalence [95%CI] was 39.4% [36.2-42.8] by FLI, 27.2% [24.2-30.4] by LAP, and 23.5% [20.7-26.5] by their combination. The prevalence progressively increased with increasing body mass index. Less smoking, and more moderate-vigorous physical activity and whole-grain consumption were associated with lower odds of having NAFLD, independently of body mass index. At least one out of four adults in Chile is afflicted with NAFLD. Health promotion strategies focused on controlling excess body weight and promoting specific lifestyle habits are urgently required.
dc.format.extent11 páginas
dc.fuente.origenORCID
dc.identifier.doi10.1017/S0007114523000028
dc.identifier.eissn14752662
dc.identifier.issn1475-2662
dc.identifier.pubmedid36620945
dc.identifier.scopusidSCOPUS_ID:85146176572
dc.identifier.urihttp://journals.cambridge.org/BJN
dc.identifier.urihttps://doi.org/10.1017/S0007114523000028
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/88300
dc.information.autorucDepartamento de Ciencias de la Salud; Pettinelli Rocha, Paulina Pilar; S/I; 1011132
dc.information.autorucDepartamento de Ciencias de la Salud; Fernández Mincone, Tiziana; 0000-0002-0865-9198; 205468
dc.information.autorucDepartamento de Ciencias de la Salud; Aguirre Polanco, Carolina; 0000-0002-5573-9000; 1012275
dc.information.autorucEscuela de Medicina; Barrera Martínez, Francisco José; 0000-0001-5334-1528; 14816
dc.information.autorucEscuela de Medicina; Riquelme Pérez, Arnoldo; 0000-0002-8259-8960; 3538
dc.issue.numero6
dc.language.isoen
dc.nota.accesosin adjunto
dc.pagina.final1046
dc.pagina.inicio1036
dc.relation.ispartofBritish Journal of Nutrition
dc.revistaBritish Journal of Nutrition
dc.rightsacceso cerrado
dc.subjectDiet
dc.subjectExercise
dc.subjectObesity
dc.subjectPublic health
dc.subjectSmoking
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titlePrevalence of non-alcoholic fatty liver disease and its association with lifestyle habits in adults in Chile. A cross-sectional study from the National Health Survey 2016-2017
dc.typeartículo
sipa.codpersvinculados1011132
sipa.codpersvinculados205468
sipa.codpersvinculados1012275
sipa.codpersvinculados14816
sipa.codpersvinculados3538
sipa.trazabilidadSCOPUS;02-03-2023
sipa.trazabilidadORCID;2024-10-21
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