Vitamin D-A prominent immunomodulator to prevent COVID-19 infection

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dc.catalogadorpva
dc.contributor.authorAshique, Sumel
dc.contributor.authorGupta, Kirti
dc.contributor.authorGupta, Gaurav
dc.contributor.authorMishra, Neeraj
dc.contributor.authorSingh, Sachin Kumar
dc.contributor.authorWadhwa, Sheetu
dc.contributor.authorGulati, Monica
dc.contributor.authorDureja, Harish
dc.contributor.authorZacconi, Flavia C. M.
dc.contributor.authorOliver, Brian G.
dc.contributor.authorPaudel, Keshav Raj
dc.contributor.authorHansbro, Philip M.
dc.contributor.authorChellappan, Dinesh Kumar
dc.contributor.authorDua, Kamal
dc.date.accessioned2023-08-22T18:14:12Z
dc.date.available2023-08-22T18:14:12Z
dc.date.issued2023
dc.description.abstractCOVID-19 remains a life-threatening infectious disease worldwide. Several bio-active agents have been tested and evaluated in an effort to contain this disease. Unfortunately, none of the therapies have been successful, owing to their safety concerns and the presence of various adverse effects. Various countries have developed vaccines as a preventive measure; however, they have not been widely accepted as effective strategies. The virus has proven to be exceedingly contagious and lethal, so finding an effective treatment strategy has been a top priority in medical research. The significance of vitamin D in influencing many components of the innate and adaptive immune systems is examined in this study. This review aims to summarize the research on the use of vitamin D for COVID-19 treatment and prevention. Vitamin D supplementation has now become an efficient option to boost the immune response for all ages in preventing the spread of infection. Vitamin D is an immunomodulator that treats infected lung tissue by improving innate and adaptive immune responses and downregulating the inflammatory cascades. The preventive action exerted by vitamin D supplementation (at a specific dose) has been accepted by several observational research investigations and clinical trials on the avoidance of viral and acute respiratory dysfunctions. To assess the existing consensus about vitamin D supplementation as a strategy to treat and prevent the development and progression of COVID-19 disease, this review intends to synthesize the evidence around vitamin D in relation to COVID-19 infection.
dc.fechaingreso.objetodigital2023-08-22
dc.fuente.origenWOS
dc.identifier.doi10.1111/1756-185X.14477
dc.identifier.eissn1756-185X
dc.identifier.issn1756-1841
dc.identifier.urihttps://doi.org/10.1111/1756-185X.14477
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/74448
dc.identifier.wosidWOS:000875731100001
dc.information.autorucEscuela de Química; Zacconi, Flavia C. M.; 0000-0002-3676-0453; 1011127
dc.issue.numero1
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.final30
dc.pagina.inicio13
dc.publisherWILEY
dc.revistaInternational Journal of Rheumatic Diseaseses_ES
dc.rightsacceso abierto
dc.rights.licenseAttribution 4.0 International (CC BY 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectDoseses_ES
dc.subjectImmune systemes_ES
dc.subjectMechanismes_ES
dc.subjectSevere acute respiratory syndrome coronavirus 2es_ES
dc.subjectVitamin Des_ES
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleVitamin D-A prominent immunomodulator to prevent COVID-19 infectiones_ES
dc.typeartículo
dc.volumen26
sipa.codpersvinculados1011127
sipa.indexWOS
sipa.trazabilidadWOS;2023-01-17
sipa.trazabilidadORCID;2023-08-21
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