Coryneform Bacteria in Granulomatous Lobular Mastitis: Morphological Diagnosis in Breast Biopsies

dc.contributor.authorOddo, David
dc.contributor.authorStefanelli, Angeles
dc.contributor.authorVillarroel, Alejandra
dc.contributor.authorMendez, Gonzalo P.
dc.date.accessioned2025-01-23T21:14:50Z
dc.date.available2025-01-23T21:14:50Z
dc.date.issued2019
dc.description.abstractGranulomatous lobular mastitis is a rare disease whose origin is still unknown and shows an increase in its frequency. Morphological, microbiological, and molecular biology studies have linked this disease to lipophilic and fastidious corynebacteria, suggesting its possible infectious etiology. This series describes and reviews in detail the distinctive morphological characteristics of the bacteria present in the granulomas of this disease, the usefulness of histochemical techniques for their identification, and our proposal for a tissue quantification score for the bacteria. The MacCallum-Goodpasture method of Gram's stain turned out to be the gold standard for examination, but we also highlight the efficiency of hematoxylin and eosin stain when it is exhaustively examined as well as the Grocott stain to evaluate the bacterial pleomorphism method, which is often underutilized.
dc.fuente.origenWOS
dc.identifier.doi10.1177/1066896918815580
dc.identifier.eissn1940-2465
dc.identifier.issn1066-8969
dc.identifier.urihttps://doi.org/10.1177/1066896918815580
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/101057
dc.identifier.wosidWOS:000468938700004
dc.issue.numero4
dc.language.isoen
dc.pagina.final386
dc.pagina.inicio380
dc.revistaInternational journal of surgical pathology
dc.rightsacceso restringido
dc.subjectgranulomatous lobular mastitis
dc.subjectcoryneform lipophilic bacteria
dc.subjectpathological diagnosis
dc.subjectGram and Grocott stains
dc.subjectbreast inflammation
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleCoryneform Bacteria in Granulomatous Lobular Mastitis: Morphological Diagnosis in Breast Biopsies
dc.typeartículo
dc.volumen27
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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